A Chinese cross-sectional study on depression and anxiety symptoms in patients with psoriasis vulgaris

Tian, Zhenfu; Huang, Yike; Yue, Tao; Zhou, Jing; Lu, Tianlan; Han, Ling; Yan, Kexiang; Huang, Qiong; Zhang, Zhenghua; Shao, Chunhong

doi:10.1080/13548506.2018.1529323

Cited by 24 publications

(36 citation statements)

References 37 publications

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“…Therefore, patients are prone to insomnia and decreased quality of life compared with the control group as pruritus of the skin lesions manifested more at night. Thus Female patients with psoriasis are more likely to suffer from depression [17,18], which is consistent with Tian Z et al [19] 's on Chinese people, suggesting that there was no significant difference in depression among patients with psoriasis on different sexes. Comparing national conditions at home and abroad could be found that the number of patients with psoriasis is almost equal between men and women beyond the seas [20].…”

Section: Discussionsupporting

confidence: 86%

“…The study found that psoriasis patients with a long course were more prone to depression than those with a short course, which was the same with the result of Lakshmy et al [22] Moreover, it has also been reported that psoriasis patients with short course are more prone to depression than those with long course, such as the study of Tian Z et al [19] Repeated attacks of the disease often turn initial hopes of a cure into disappointment. Repeated visits to the doctor often lead to anxiety and, over time, depression.…”

Section: Discussionsupporting

confidence: 80%

“…Tian Z et al [19] believed that the onset of depression among psoriasis vulgaris was not related to age, but was related to the age at which psoriasis occurred. Conversely, the result of the study showed that older patients had a higher prevalence of depression.…”

Section: Discussionmentioning

confidence: 99%

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Correlation of Catecholamine Content and Clinical Influencing Factors in Depression among Psoriasis Patients: A Case-Control Study

Shu

Fang

Xia

et al. 2020

Preprint

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Backgroud: This study sought to investigate the clinical influencing factors of patients with psoriasis vulgaris complicated with depression, and to analyze whether the content of monoamine neurotransmitters in plasma was correlated with depression incidence among psoriasis patients. Methods Ninety patients aged 18-60 years with psoriasis vulgaris referred to the dermatology department and 40 healthy volunteers aged 18-60 years referred to the physical examination center of the Affiliated Hospital of Southwest Medical University were included. Questionnaires were administered in both groups to obtain basic patient information, Hamilton Depression Scale(HAMD), and Athens Insomnia Scale(AIS) scores. The questionnaire only for patients with psoriasis vulgaris included the course of disease, Psoriasis Area and Severity Index (PASI), and Dermatology Life Quality Index (DLQI). The catecholamine in plasma from the two groups was analyzed by radioimmunoassay. The data were analyzed by SPSS statistical software. Results: The mean HAMD (P=0.034) and mean AIS scores (P=0.001) of the psoriasis patients were higher than those of the control group, while the mean content of dopamine (P=0.004) and adrenaline in the plasma (P=0.007) of the psoriasis group were lower than those of the control group. Dopamine content in the plasma was lower (comparing psoriasis patients without depression and the control group: P<0.001), and was negatively correlated with HAMD, (P<0.05), AIS (P<0.05), and PASI scores (P<0.05) in the psoriasis patients with depression. There was no significant difference in the epinephrine and norepinephrine contents in all groups. PASI scores were positively correlated with HAMD scores in patients with psoriasis vulgaris, and the mean dopamine content in the patients with depression (P=0.001) was significantly lower than in those without depression. The low dopamine content and high PASI and DLQI scores were the risk factors for depression among the patient population. Conclusion: Psoriasis patients have a significantly higher risk of depression than healthy people, and higher PASI scores were linked to a higher incidence of depression. The dopamine levels of patients were influenced by both psoriasis and depression. The risk factors for depression in psoriasis patients are low dopamine levels in the plasma, severe skin lesions, and lower quality of life.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 80%

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Correlation of Catecholamine Content and Clinical Influencing Factors in Depression among Psoriasis Patients: A Case-Control Study

Shu

Fang

Xia

et al. 2020

Preprint

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“…Cut points of 5, 10, 15, and 20 were used to generate categorical description of depression severity, where the score was interpreted as the patient is having no or minimal (0-4), mild (5-9), moderate (10)(11)(12)(13)(14), moderately severe (15)(16)(17)(18)(19), or severe depression (20)(21)(22)(23)(24)(25)(26)(27). Because a score of ≥ 10 indicated that pharmacotherapy should be considered, it was used as the cut point for calculating the prevalence of depression.…”

Section: Patient Health Questionnaire-9 (Phq-9)mentioning

confidence: 99%

“…The patients responded to each question on a 0-4 scale, from less to more severe, generating a score of 0-28. The score was interpreted as the patient is having no clinically significant insomnia (0-7), mild insomnia (8)(9)(10)(11)(12)(13)(14), moderate insomnia (15-21), or severe insomnia (22)(23)(24)(25)(26)(27)(28). Because a cut-off score of ≥ 10 is optimal for detecting insomnia in a community sample [25], it was used as the cut point for calculating the prevalence of insomnia.…”

Section: Insomnia Severity Index (Isi)mentioning

confidence: 99%

Depressive, anxiety, stress, and insomnia symptoms in patients with psoriasis: a cross-sectional study

Soliman¹

2021

pdia

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Introduction: Assessment of psychological well-being in psoriasis patients is recommended. However, studies evaluating depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis are lacking. Aim: To quantify levels of psoriasis-related depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis. Material and methods: A cross-sectional survey on patients' demographics, disease characteristics, and psychological measures using the Patient Health Questionnaire-9, Generalized Anxiety Disorder 7-item scale, Depression Anxiety Stress Scale-21 (7-item stress subscale), and Insomnia Severity Index. The prevalence and scores of depressive, anxiety, stress, and insomnia symptoms were calculated. Multivariate linear regression models were developed to assess patients' demographics and disease characteristics affecting the psychological measures. Results: The analysis included 223 patients. The patients reported mild levels of depressive, anxiety, and insomnia symptoms (median (interquartile range (IQR)) scores: 9 (6-14), 6 (4-11), and 12 (4-18), respectively) and a moderate level of stress symptoms (median (IQR) score: 10 (5-14)). The prevalence of depressive, anxiety, stress, and insomnia symptoms were 47.1%, 32.7%, 59.6%, and 57%, respectively. Multivariate linear regression analyses revealed that for each unit increase in the impact of psoriasis on daily life, there were 5.7 (95% confidence intervals (CI): 3.7-7.8), 3.8 (95% CI: 1.8-5.7), 5.3 (95% CI: 3.1-7.4), and 6.5 (95% CI: 3.7-9.4) units increase in depression, anxiety, and stress, and insomnia scores, respectively. Conclusions: The prevalence of depressive, anxiety, stress, and insomnia symptoms in Arabic patients with psoriasis was high. Clinical interventions, screening for psychiatric comorbidities, and consideration of psychotherapy should be implemented in this patient group.

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Cognitive deficiency, parental relationship, and coping strategies are related with anxiety and depression among parents of children with epilepsy

Ren

Yang

2022

Chronic Diseases and Translational Medicine

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Background: The diagnosis of epilepsy in a child often and understandably causes psychological adjustment difficulties in the parents. To help parents of children with epilepsy cope with stress, it is important to understand how parents cope with the sickness of their child. The objective of this study was to assess factors related to the state of anxiety and depression among parents of children with epilepsy. Methods: The present study was a cross-sectional study, and the data were collected through an anonymous, Internet-based survey platform between October 2018 and October 2019 from 250 participants aged 22-65 years. Participants were invited to fill questionnaires include socioeconomic questionnaire, anxiety, depression, and coping strategies scale. Result: Among the parents of children with epilepsy, 48.8% (122/250) had depressive symptoms (Patient Health Questionnaire-9 [PHQ-9] score >4) and 46.4% (116/250) had anxiety symptoms (7-item Generalized Anxiety Disorder [GAD-7] score >5). Depression among parents of children with epilepsy was significantly associated with comorbidity (odds ratio [OR] = 0.392, 95% CI = 0.182-0.846), a poor parental relationship (OR = 0.283, 95% CI = 0.130-0.614), positive coping (OR = 0.947, 95% CI = 0.903-0.992), and negative coping (OR = 1.287, 95% CI = 1.179-1.405). Anxiety among parents of children with epilepsy was significantly associated with a poor parental relationship (OR = 0.416, 95% CI = 0.207-0.835) and negative coping (OR = 1.155, 95% CI = 1.087-1.228). Conclusions: The present study indicates the importance of couple support and providing effective coping to make parents of children with epilepsy more resilient in the presence of negative life events, especially for parents of children with comorbidity with cognitive deficiency. K E Y W O R D S combability, coping strategies, couple relationship, epilepsy, parents Highlights • Parents of children with epilepsy are at high risk of experiencing anxiety and depression.

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A Chinese cross-sectional study on depression and anxiety symptoms in patients with psoriasis vulgaris

Cited by 24 publications

References 37 publications

Correlation of Catecholamine Content and Clinical Influencing Factors in Depression among Psoriasis Patients: A Case-Control Study

Correlation of Catecholamine Content and Clinical Influencing Factors in Depression among Psoriasis Patients: A Case-Control Study

Depressive, anxiety, stress, and insomnia symptoms in patients with psoriasis: a cross-sectional study

Cognitive deficiency, parental relationship, and coping strategies are related with anxiety and depression among parents of children with epilepsy

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