A Child With Lacrimal Gland Swelling

Karia, Vijay R.; Shah, Neel; Espinoza, Luis R.; Gedalia, Abraham

doi:10.1177/0009922809340503

Cited by 1 publication

(1 citation statement)

References 8 publications

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“…The lacrimal glands are the most commonly involved orbital structures in sarcoidosis, with reported prevalence of 42–63% in studies of orbital and ocular adnexal sarcoidosis [ 7 – 9 ], and 7–16% in systemic disease [ 9 ]. Lacrimal gland involvement has been reported in pediatric sarcoidosis [ 2 , 10 – 12 ], but our literature search found no published estimates of prevalence based on histopathologic diagnosis. Granulomatous disease of the lacrimal glands without systemic involvement has also been described in adults, but there is no literature to estimate prevalence of this occurrence in children.…”

Section: Discussionmentioning

confidence: 89%

Sarcoidosis presenting as bilateral lacrimal gland swelling: a pediatric case report

et al. 2021

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Background To describe a case of pediatric sarcoidosis which initially presented as papillary conjunctivitis before manifesting as bilateral lacrimal gland swelling without other known systemic involvement. Case presentation A 10-year-old female presented to the pediatric ophthalmology clinic with complaints of bilateral eyelid swelling, tearing and itching for approximately 1 month. Her history and exam were most consistent with allergic conjunctivitis, for which she was started on a standard topical regimen. Despite initial improvement, she re-presented with significantly worsened eyelid swelling and minimal allergic symptoms. Enlargement of the lacrimal glands were palpable at this time. Lacrimal gland biopsy was obtained which demonstrated noncaseating granulomas. Systemic workup did not reveal evidence of disease involvement elsewhere. Conclusions Sarcoidosis in the pediatric population may present in a myriad of ways and is well-known to mimic other disease entities. We present a case of pediatric sarcoidosis which presented initially as papillary conjunctivitis before manifesting as bilateral lacrimal gland swelling without systemic involvement.

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