A chemical investigation ofAchillea nobilis

Адекенов, С. М.; Mukhametzhanov, M. N.; Кагарлицкий, А. Д.; Турмухамбетов, А. Ж.

doi:10.1007/bf00580067

Cited by 9 publications

(9 citation statements)

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“…2',4',6'-Trihydroxy-3'-prenyl-chalcone (7) was first found in Pleiotaxis rugosa [21], then in Heli chrysum athrixiifolium [22] and in H. rugulosum [20]. 3,5-Dihydroxy-6,7,8-trimethoxy flavone (8) was reported previously from Helichrysum arenarium [23], Achryrocline bogotensis [24], Achillea nobilis [25], Helichrysum decumbens [18].…”

Section: Discussionmentioning

confidence: 96%

“…int.) 330 (79, M +; C 17H 140 7), 315 (100), 287(36), 272(21), 105 (40), 77 (57), 69(25). The mass spectrum indicated this flavonoid to be a flavone/flavonol with three hy droxy and two methoxy groups, for which the in tensity o f [M -1 5 ]+ suggested 8-OM e-substitution in accord with two methoxy and the hydroxy sig nals which appeared in the 'H N M R spectrum.…”

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confidence: 99%

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Rare Flavonoid Aglycones from Anaphalis margaritacea and Two Gnaphalium Species

Wollenweber

Fritz

Henrich

et al. 1993

Zeitschrift Für Naturforschung C

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Section: Discussionmentioning

confidence: 96%

mentioning

confidence: 99%

Rare Flavonoid Aglycones from Anaphalis margaritacea and Two Gnaphalium Species

Wollenweber

Fritz

Henrich

et al. 1993

Zeitschrift Für Naturforschung C

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“…1,4--endoperoxyguaianolides may be the most significant components of A. distans [37] while 11,13-dehydrodeacetylmatricarin was found as major constituent of A. pannonica [38] and of A. setacea [39]. Research of the last period reveals more and new guaianolid compounds, like 8 -hydroxy-tanaparthin--peroxide from A. setacea [39], or anobin in A. nobilis [40].…”

Section: Guaianolidesmentioning

confidence: 95%

“…Special flavon derivatives were described in individual species like quercetagetin-6, 7, 3', 4'-tetramethyl ether and diosmetin in A. collina, acacetin in A. distans [43], 3, 5-dioxy-6, 7, 8-trimethoxyflavone in A. nobilis [40].…”

Section: Fig (5) Main Flavonoid Sceleton Of Yarrowsmentioning

confidence: 99%

Biological Activities of Yarrow Species (Achillea spp.)

Németh

Bernáth

2008

CPD

135

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The genus Achillea consists of about 140 perennial herbs native to the Northern hemisphere. Traditional indications of their use include digestive problems, liver and gall-bladder conditions, menstrual irregularities, cramps, fever, wound healing. The Commission E approves its internal use for loss of appetite and dyspeptic ailments (gastric catarrh, spastic discomfort), externally it is used in form of sitz bath or as a compress against skin inflammation, slow healing wounds, bacterial or fungal infections. In the last decades, pharmacological studies became intensive, although human clinical investigations are still rare. Recent findings have confirmed several traditional uses. The largest number of data accumulated for antioxidant and anti-inflammatory effects. There are positive results on the analgesic, anti-ulcer, choleretic, hepatoprotective and wound healing activities. First results on other interesting therapeutical areas - antihypertensive, antidiabetic, antitumor, antispermatogenic activities -need confirmation. Yarrow can be used also as an insect repellent. Contact dermatitis as adverse effect may be connected to sesquiterpenes. The diversity and complexity of the effective compounds of yarrow species explains the broad spectrum of their activity. According to the literature the pharmacological effects are mainly due to the essential oil, proazulenes and other sesquiterpene lactones, dicaffeoylquinic acids and flavonoids. Synergistic actions of these and other compounds are also supposed. Achillea species have different chemical and therapeutical values. Despite of numerous data, correct evaluation of the results is difficult because of missing generally accepted taxonomical nomenclature. The used chemical-analytical methods and bio-assays are utmost diverse, making the comparison complicated. Further research on the activity is needed using exactly defined plant material, standardized methods and chemical analysis.

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“…Mass spectra (EI, 70 eV) were obtained in a Finnigan MAT 8200 instrument. Estafiatin (1) used for the reactions was isolated from the aerial part of Achillea nobilis L. [9].…”

Section: Methodsmentioning

confidence: 99%