A Cephalometric Analysis of Maxillary and Mandibular Parameters in Treacher Collins Syndrome

Abstract

This study quantifies the cephalometric dysmorphology of patients with Treacher Collins syndrome and compares it to that of age-matched controls. These cephalometric characteristics have clinical significance in Treacher Collins syndrome and in the planning of bimaxillary advancement and genioplasty in syndrome patients.

Planning Surgical Reconstruction in Treacher-Collins Syndrome Using Virtual Simulation

“…Other authors have also suffered from groups of patients not truly representative of the TreacherCollins syndrome population and low sample sizes because of the rarity of the condition. 1,17,21 We have shown that geometric morphometrics still has a role in the severely affected child with absent zygomatic arches or complete absence of the orbitozygomatic region. If there is unilateral absence of the orbitozygomatic region secondary to trauma or malignancy, surgeons have used the contralateral normal facial skeleton to design a size-matched zygoma or absent temporomandibular joint process.…”

“…Previous studies have described Treacher-Collins syndrome skull morphology either with cephalography, qualitative analysis using three-dimensional computed tomographic head scans, or volume analysis. 1,[15][16][17][18][19][20] They all use traditional morphometric techniques, which measure lengths, angles, and volumes and relate them to specific defects. However, none of these tools can provide a global picture of the Treacher-Collins syndrome deformity.…”

“…1). 1 Congenital craniofacial anomalies may have significant functional and psychological impact on children, and appropriate presurgical planning in reconstructive surgery can have a profound impact on quality of life. 2 Geometric morphometrics will also help us understand the craniofacial shape variations seen in Treacher-Collins syndrome and how best to correct deformities with surgical procedures available today.…”

The characteristics of craniofacial and cervicovertebral morphology in different genetic syndromes: A literature review and three case reports

“…The most severe forms of TCS may have significantly deficient proximal mandible or even lacking the ramus/condyle unit altogether. 33,34,[39][40][41] Hypoplasia of the facial bones may result in dental malocclusion. The teeth may be widely spaced, malpositioned or reduced in number.…”

Refinamento fenotípico da disostose mandibulofacial tipo Bauru

“…Na presente casuística, a altura facial total mostrou-se reduzida e a altura ântero-inferior, aumentada, o que difere do observado na STC. Chong et al (2008), comparando dados cefalométricos de 24 adolescentes com STC com dados obtidos do grupo controle (pareado pelo gênero), observaram que a dimensão da maxila na STC é reduzida e a mandíbula é pequena e significativamente rodada para baixo e para trás. De acordo com os autores, a alteração mandibular é responsável pelo perfil facial convexo observado na STC.…”