A Centennial: George W. Beadle, 1903–1989

Horowitz, N. H.; Berg, Paul; Singer, Maxine; Lederberg, Joshua; Susman, Millard; Doebley, John; Crow, James F.

doi:10.1534/genetics.166.1.1

Cited by 9 publications

(5 citation statements)

References 26 publications

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“…Caltech then reinvented itself under George Beadle in 1946 (Horowitz et al 2004) by recruiting a range of geneticists including Max Delbruck, who created a bacteriophage "church." My article, "Paradox Found" (Dove 1987), described the philosophical culture generated by Delbruck, the intellectual impact of the physicist Richard Feynman, and the doctoral research of the afore-mentioned Charley Steinberg.…”

Section: Caltechmentioning

confidence: 99%

Weaving a Tapestry from Threads Spun by Geneticists: The Series Perspectives on Genetics, 1987–2008

Dove

2016

Genetics

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The Perspectives column was initiated in 1987 when Jan Drake, Editor-in-Chief of GENETICS, invited Jim Crow and William Dove to serve as coeditors of "Anecdotal, Historical, and Critical Commentaries." As the series evolved over 21 years, under the guidance of Crow and Dove, the input of stories told by geneticists from many countries created a panorama of 20th-century genetics. Three recurrent themes are visible: how geneticists have created the science (as solitary investigators, in pairs, or in cooperative groups); how geneticists work hard, but find ways to have fun; and how public and private institutions have sustained the science of genetics, particularly in the United States. This article ends by considering how the Perspectives series and other communication formats can carry forward the core science of genetics from the 20th into the 21st century.

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Section: Caltechmentioning

confidence: 99%

Weaving a Tapestry from Threads Spun by Geneticists: The Series Perspectives on Genetics, 1987–2008

Dove

2016

Genetics

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“…Members of this phylum reproduce sexually or meiotically via the production of non-motile ascospores inside a microscopic sac-like structure called an ascus, the defining feature of this group of fungi. Because the products of meiosis-the ascosporesare retained within the ascus, ascomycetes such as Neurospora crassa have been used-as mentioned before-for elucidating the principles of genetics and heredity [18]. Many species of Ascomycota also (or exclusively) produce spores called conidia through an asexual or mitotic process [52].…”

Section: Taxonomymentioning

confidence: 99%

“…Another landmark model fungal species for scientific research was the pink mold Neurospora crassa. Studies with this organism revealed for the first time that genes control the expression of enzymes and that one gene regulates one enzyme [18].…”

Section: Introductionmentioning

confidence: 99%

Traditional Plant-Based Treatments of Fungal Infections in the Republic of Suriname (South America): Phytochemical and Pharmacological Rationales

Mans¹

2022

Traditional Plant-Based Forms of Treatment of Fungal Infections in Suriname - Phytochemical and Pharmacological Rationale

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Fungi are unicellular or multicellular thick-walled eukaryotic organisms that are not capable of photosynthesis and are placed in a biological kingdom of their own. They are ubiquitous in our environment, and include tens of thousands, perhaps even millions of species of yeasts, rusts, smuts, mildews, molds, and mushrooms. Together with bacteria, fungi are the principal decomposers of plant materials such as cellulose and lignin, fulfilling vital ecological functions in all terrestrial habitats. Some species of fungi are also of major importance in households (for instance, as foods such as edible mushrooms), medicine (for instance, as producers of antibiotics such as penicillin), and industry (for instance, for making bread, wine, and cheese). About 300 fungal species cause infections in humans, varying from relatively harmless skin complaints such as pityriasis versicolor to potentially life-threatening systemic syndromes such as candidiasis. Fortunately, a broad armamentarium of efficacious antifungal drugs has been developed, ranging from topical nystatin to parenteral amphotericin B. In addition, most, if not all traditional medical systems throughout the world have identified a large assortment of plant-based remedies for treating these infections. This also holds true for the multi-ethnic and multicultural Republic of Suriname (South America), where plant-based traditional medicines are abundantly used, either alone or in conjunction with allopathic medications. This monograph extensively addresses nine plants that are traditionally used for treating fungal infections in Suriname, and explains the phytochemical and pharmacological rationales for these applications. These sections are preceded by some general observations about the Fungal Kingdom; a few words about the characteristics of fungi, their taxonomy, and their significance to humans; information about fungal infections as well as the available forms of treatment; and some details about Suriname including health aspects, the health care structure, and the main fungal infections in the country. The monograph is concluded with an evaluation of the status of the Surinamese herbal antifungal substances and the previsions of developing them into mainstream antifungal formulations.

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“…4 To dynamically test the system a pseudo-random noise source (PRNS) was connected to the input of each of the Series A amplifiers. The PRNS is based on the output of a Linear Feedback Shift Register (LFSR) as described by [7] which is then filtered with a programable raised cosine 10-th order low pass filter. The signal level, cycle rate and clock frequency can be adjusted.…”

Section: Measurement Examples 41 Multiple Channel Data Acquisition mentioning

confidence: 99%

Dynamic Testing of Data Acquisition Channels Using the Multiple Coherence Function

Richards¹

2012

Data Acquisition Applications

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The idea of inputting a white noise signal into two A/D converters and computing the residual spectra from the ordinary coherence function, in order to characterize the noise of the devices was first reported in [19], and that concept was extended to testing multiple A/D converters using the multiple coherence function in [20]. In this chapter, those methods are expanded to encompass the entire data acquisition channel, so that dynamic testing of multiple amplifiers, filters or A/D converters can be performed. no window Chan. σ e (µV) σ n (µV) CB σ e (µV) σ n (µV) CB σ e (µV) σ n (µV) CB σ e (µV) σ n (µV) CB

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A Centennial: George W. Beadle, 1903–1989

Cited by 9 publications

References 26 publications

Weaving a Tapestry from Threads Spun by Geneticists: The Series Perspectives on Genetics, 1987–2008

Weaving a Tapestry from Threads Spun by Geneticists: The Series Perspectives on Genetics, 1987–2008

Traditional Plant-Based Treatments of Fungal Infections in the Republic of Suriname (South America): Phytochemical and Pharmacological Rationales

Dynamic Testing of Data Acquisition Channels Using the Multiple Coherence Function

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