A cation exchange resin bead-based microscale electrolytic suppressor for capillary ion chromatography

Zhang, Feifang; Li, Yapu; Yang, Bingcheng; Liang, Xinmiao

doi:10.1016/j.talanta.2010.11.043

Cited by 8 publications

(2 citation statements)

References 18 publications

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“…4,5 Many difficulties associated with capillary IC have only been addressed very recently to the extent where commercially available systems could be marketed. Some of these challenges lay in the provision of stationary phases with sufficient capacity and efficiency for small ion separations; [6][7][8] the development of capillary suppressor technologies for use with conductivity detection; 2,9,10 and the development of suitable IC detection modes which can operate sensitively at the micro-scale level. [11][12][13][14] Furthermore, the use of capillary zone electrophoresis (CZE) has long dominated capillary-scale separations of small ions by comparison and has shown to be particularly useful in forensic applications especially for samples of limited size.…”

Section: Introductionmentioning

confidence: 99%

Probing gunshot residue, sweat and latent human fingerprints with capillary-scale ion chromatography and suppressed conductivity detection

Gilchrist

Smith

Barron

2012

Analyst

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An investigation into capillary-scale ion chromatography with suppressed conductivity detection is presented for the identification of low molecular weight anions in samples of limited size. Both particle-packed and polymer monolith capillary ion exchange resins were compared with respect to their chromatographic efficiencies, operating back-pressures and thermal selectivities. Using a multistep hydroxide gradient, it was possible to separate a large selection of inorganic and organic anions in <23 mins using both phases with an injection volume of only 0.4 μL. Method performance was tested with respect to linearity, range, reproducibility and sensitivity and compared to a micro-bore (2 mm) IC method. Limits of mass sensitivity improved by factors up to 1,800-fold using the capillary IC system and lay in the range 0.3-26.2 pg. The finalised analytical method was applied to the determination of both endogenous and exogenous species in sweat and fingermark deposits. It was possible to determine presence of elevated levels of thiocyanate and benzoate in the sweat of three moderate smokers (5-10 cigarettes/day) in comparison to non-smokers. A controlled firing experiment was also conducted to assess the transfer of gunshot residue into fingerprints of a firer. Similarly, identification of direct contact with a black powder substitute is presented via analysis of latent fingermarks. To the best of our knowledge, this represents the first study of sweat and fingerprints using capillary-scale suppressed ion chromatography.

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Section: Introductionmentioning

confidence: 99%

Probing gunshot residue, sweat and latent human fingerprints with capillary-scale ion chromatography and suppressed conductivity detection

Gilchrist

Smith

Barron

2012

Analyst

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“…Recently, these suppressor technologies have been applied to capillary IC using the capillary column as a separation column, and a suppressor for capillary IC has also been developed. [14][15][16][17] A continuously and electrolytically regenerated packed-bed suppressor (known as Atlas) was made available by Dionex in 2001, which operates with high eluent concentrations, and has a very low dead volume. 10 Other devices, called electrically regenerated ion suppression (ERIS) 7,8 cells and the DS-Plus suppressor, 11 have been introduced by Alltech.…”

Section: Introductionmentioning

confidence: 99%

Development of a New Suppressor for the Ion Chromatography of Inorganic Cations

et al. 2014

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This paper reports on a new suppressor that can be used in the ion chromatography (IC) of inorganic cations. The space in which the electrode is set on both sides of the device is separated into three cells using anion-and cation-exchange membranes. Each of the cells is packed with either an anion-or cation-exchange resin. Anions in the eluent and injected sample are removed by electrical regeneration, based on the electrokinetic phenomenon on both the surface of the ion-exchange resins and the membranes. The electrical conductivity of the suppressed eluent reaches a level similar to that of ultrapure water; therefore, a cation detection limit of sub-ppb order is achieved in IC using the device as a suppressor.

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