“…4 The broad spectrum in which melioidosis can manifest ranges from pneumonia, skin lesions, internal abscesses, and sepsis to mild respiratory distress, making clinical diagnosis incredibly difficult. 1,2,5 In addition to the challenges of diagnosis rate, B. pseudomallei is intrinsically resistant to many antibiotics, with many conventional antibiotic treatments having only a bacteriostatic effect. 6 In addition, effective treatment requires long-term intravenous and oral antibiotic treatment regimens that are challenging to implement in many endemic countries due to poor adherence, flexible antibiotic administration, and low treatment affordability.…”