A Case Report of Wernicke's Encephalopathy Associated With Schizophrenia

He, Jingqi; Li, Jinguang; Li, Zhijun; Ren, Honghong; Chen, Xiaogang; Tang, Jinsong

doi:10.3389/fpsyt.2021.657649

Cited by 3 publications

(2 citation statements)

References 29 publications

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“…The positive symptoms, delusions and hallucinations -e.g., hearing commands to desist from certain foods or avoid certain grocery stores for fear of danger -may deprive patients with schizophrenia of specific foods. Occasional case reports attest to this possibility-these are reports of Wernicke's thiamine deficiency and encephalopathy associated with schizophrenia (in the absence of alcohol consumption) [23][24][25][26][27][28]. Alcohol addiction may, nonetheless, in many cases of schizophrenia, be the main cause of Wernicke's syndrome [29].…”

Section: Schizophrenia Symptomsmentioning

confidence: 99%

Women with Schizophrenia Have Difficulty Maintaining Healthy Diets for Themselves and Their Children: A Narrative Review

Seeman

2023

Behavioral Sciences

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Severe psychiatric disorders such as schizophrenia are inevitably linked to unemployment, meagre per capita income, and residence in disadvantaged, poorly resourced neighbourhoods. This means difficult access to healthy food and is particularly problematic for pregnant women and mothers with children to feed. The necessity of taking antipsychotic drugs is an additional barrier to healthy eating because these drugs are associated with serious cognitive, psychological, behavioural, and metabolic sequelae. Being ill with psychosis makes it extremely difficult to maintain a healthy diet; nutritional deficiencies result, as do medical complications. The results of present literature review confirm the gravity of the problem and suggest a number of potentially useful clinical interventions.

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Section: Schizophrenia Symptomsmentioning

confidence: 99%

Women with Schizophrenia Have Difficulty Maintaining Healthy Diets for Themselves and Their Children: A Narrative Review

Seeman

2023

Behavioral Sciences

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show abstract

“…hearing commands to desist from certain foods or avoid certain grocery stores for fear of danger, may deprive patients with schizophrenia of specific foods. Occasional case reports a est to this possibility -these are reports of Wernicke's thiamine deficiency and encephalopathy associated with schizophrenia (and absence of alcohol consumption) [23][24][25][26][27][28]. Alcohol addiction may, nonetheless, in many cases of schizophrenia, be the main cause of Wernicke's syndrome [29].…”

Section: Scizophrenia Symptomsmentioning

confidence: 99%

Nutrition in Schizophrenia

Seeman

2023

Preprint

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Severe mental illness such as schizophrenia is associated with factors such as unemployment, meagre per capita income, and residence in disadvantaged, poorly resourced neighbourhoods. This means difficult access to healthy food and is particularly problematic for pregnant women and mothers with children to feed. Eating problems are also linked to the necessity of taking antipsychotic drugs that often lead to serious cognitive, psychological, and behavioural sequelae. Psychosis makes it extremely difficult to maintain a healthy diet; nutritional deficiencies result, as do medical complications. The results of present literature review confirm the gravity of the problem and suggest a number of potentially useful interventions.

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Gayet–Wernicke encephalopathy: a complication not to be overlooked in patients with catatonic schizophrenia

Messedi

Turki

Rihab

et al. 2023

Egypt J Neurol Psychiatry Neurosurg

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Background Gayet–Wernicke's encephalopathy (GWE) is a life-threatening neurological emergency caused by vitamin B1 deficiency. This is a rare complication, which may be reversible if managed promptly. However, any diagnostic or therapeutic delay exposes to the risk of serious sequelae. Although this pathology frequently occurs in chronic alcohol users, it can also occur in any situation of severe undernutrition. In this context, we report a case of GWE occurring after severe undernutrition complicating prolonged catatonia in a patient suffering from schizophrenia. Case presentation He was a 47-year-old patient, suffering from esophageal stenosis, and followed in psychiatry for schizophrenia, who was hospitalized for a catatonic relapse. He was put on benzodiazepine with parenteral rehydration. Faced with the persistence of food refusal, and the appearance of signs of undernutrition, a parenteral diet was introduced. The evolution was marked by the deterioration of his general and neurological condition, with the appearance of mental confusion. The examination showed a central vestibular syndrome, and brain magnetic resonance imaging showed a hyperintense signaling in the periaqueductal area, in mammillary bodies, and in medial thalamic nuclei on T2-FLAIR sequences. GWE was suspected and parental vitamin B1 therapy was initiated. Laboratory testing confirmed the diagnosis, showing a low thiamine blood level of 32 nmol/l [normal range: 78 to 185 nmol/l]. Regression of neurological symptoms was observed within 2 weeks of treatment. Conclusion Through this illustration, we draw the attention of the psychiatrist, who must think about preventing this complication, by supplementing any patient at risk of developing GWE with vitamin B1.

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A Case Report of Wernicke's Encephalopathy Associated With Schizophrenia

Cited by 3 publications

References 29 publications

Women with Schizophrenia Have Difficulty Maintaining Healthy Diets for Themselves and Their Children: A Narrative Review

Women with Schizophrenia Have Difficulty Maintaining Healthy Diets for Themselves and Their Children: A Narrative Review

Nutrition in Schizophrenia

Gayet–Wernicke encephalopathy: a complication not to be overlooked in patients with catatonic schizophrenia

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