A case report of submandibular aggressive fibromatosis in a 16-month-old infant with 8-year postsurgical follow-up

Aggressive fibromatosis in the submandibular region of a child

“… 6 Involvement of head and neck is not common, and there are case reports of infantile fibromatosis involving the submandibular space. 3 , 11 Clinical presentation of the lesion as a rapidly growing swelling was consistent with the reported cases of aggressive fibromatosis. 3 , 12 , 13 , 14 Despite negative sexual predilection, most of the reported cases of aggressive fibromatosis of the mandible were young females.…”

“…Bone erosion, periosteal thickening, and even lateral bowing of mandibular ramus are reported radiographic appearances 6 . Involvement of head and neck is not common, and there are case reports of infantile fibromatosis involving the submandibular space 3,11 . Clinical presentation of the lesion as a rapidly growing swelling was consistent with the reported cases of aggressive fibromatosis 3,12–14 .…”

“… 3 , 12 , 13 , 14 Despite negative sexual predilection, most of the reported cases of aggressive fibromatosis of the mandible were young females. 3 , 11 , 12 , 14 , 15 , 16 , 17 In the current case, lesion was mainly located in buccal and inferior portions of mandible and lingual vestibule showed normal depth, while bone destruction was observed in lingual aspect of the alveolar process away from the main tumor mass. This kind of extension could be explained by periosteal extension of the lesion.…”

Pediatric fibromatosis involving mandible: case reportand a five-year post-operative follow-up

“…However, this option is difficult in patients with tumors in the head and neck region due to the anatomical complexity and the proximity of vital structures (14) . When complete resection of lesions does not occur, they have a local recurrence rate that varies between 50%-70% of cases (3,13) . In children, surgical treatment of extra-abdominal fibromatosis is even more complicated because of the potential risk of functional incapacity (11) .…”

“…Treatment of head and neck fibromatosis is complete surgical excision, in which recurrence is high when negative surgical margins are not achieved (2,13) .…”