A Case Report of Shrinking Lung Syndrome in Mixed Connective Tissue Disease

Tojino, Anna Katrina; Manua, Norhanah; Chua, Jamie; Albay, Albert B.

doi:10.1016/j.chest.2018.08.858

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2021

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“…It affects more frequently systemic lupus erythematosus (SLE) patients (approximately 1%) (2). However, this involvement has been described in other CTDs, including mixed connective tissue disease (MCTD) (1,(3)(4)(5). It is characterised by reduced lung volumes and extra-pulmonary restrictive ventilatory pattern (1,2).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of intravenous immunoglobulin in shrinking lung syndrome associated with mixed connective tissue disease: a case report

Silvério-António

Khmelinskii

Fonseca

2021

Clinical and Experimental Rheumatology

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Shrinking lung syndrome is a rare manifestation of connective tissue diseases, namely systemic lupus erythematosus. It is characterised by reduced lung volumes and extra-pulmonary restrictive ventilatory pattern with good response to high-dose glucocorticoids alone or in combination with a second immunosuppressive agent. Here, we describe a case associated with mixed connective tissue disease and effectively treated with intravenous immunoglobulin.

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