A case report of metronidazole-induced encephalopathy in a bowel obstruction patient with MRI findings

Abstract

Metronidazole is a widely used antimicrobial agent in the treatment of anaerobic and protozoal infections. However, excessive and prolonged use of metronidazole can lead to encephalopathy. We present a case of a 69-year-old male with bowel obstruction who was treated with metronidazole for approximately 26 days and subsequently developed neurological signs and symptoms. The magnetic resonance imaging findings were consistent with the suspected diagnosis of metronidazole-induced encephalopathy. This case highlights the necessity for careful monitoring of patients receiving metronidazole to detect central nervous system toxicity, and emphasizes the role of magnetic resonance imaging in confirming the diagnosis.