A Case Report of Meningeal Hemangiopericytoma: A 9-Year Journey from the Brain to the Spine

Sweid, Ahmad; Noureldine, Mohammad Hassan A.; Nasser, Selim M.; Badra, Mohammad; Saikali, Ibrahim

doi:10.1016/j.wneu.2018.11.028

Cited by 6 publications

(5 citation statements)

References 9 publications

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“…To our knowledge, this case represents only the 16th reported case in the medical literature. 10,[16][17][18][19][20][21][22][23][24][25][26][27][28][29] More common sites for metastatic spread include long bones (19.6%), lung and pleura (18.4%), and liver (17.6%). As illustrated in our case, metastasis to multiple different sites is common and occurs late with a mean time to discovery of 7.5 years.…”

Section: Discussionmentioning

confidence: 99%

Intracranial solitary fibrous tumor with delayed symptomatic metastasis to the lumbar spine: illustrative case

Menaker¹,

Ljubimov²,

Krutikova

et al. 2023

Journal of Neurosurgery: Case Lessons

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BACKGROUND Intracranial solitary fibrous tumors (SFTs), formerly known as hemangiopericytomas, are rare, aggressive mesenchymal extra-axial tumors typically treated via resection, often with preoperative embolization and postoperative radiation and/or antiangiogenic therapy. Although surgery confers a significant survival benefit, local recurrence and distant metastasis are not uncommon and may occur in a delayed fashion. OBSERVATIONS The authors describe the case of a 29-year-old male who initially presented with headache, visual disturbance, and ataxia, and was found to have a large right tentorial lesion with mass effect on surrounding structures. He underwent tumor embolization and resection with gross total resection achieved and pathology consistent with World Health Organization grade 2 hemangiopericytoma. The patient recovered well, but 6 years later presented with low back pain and lower extremity radiculopathy and was found to have metastatic disease within the L4 vertebral body causing moderate central canal stenosis. This was successfully treated with tumor embolization followed by spinal decompression and posterolateral instrumented fusion. Metastasis of intracranial SFT to vertebral bone is exceedingly rare. To our knowledge this is only the 16th reported case. LESSONS Serial surveillance for metastatic disease is imperative in patients with intracranial SFTs given their propensity and unpredictable time course for distant spread.

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Section: Discussionmentioning

confidence: 99%

Intracranial solitary fibrous tumor with delayed symptomatic metastasis to the lumbar spine: illustrative case

Menaker¹,

Ljubimov²,

Krutikova

et al. 2023

Journal of Neurosurgery: Case Lessons

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“… 4 , 5 , 12 After 10 years, given appropriate patient follow-up, there is up to a 70% chance of recurrence or metastasis with the most common sites being bone, liver, or lung. 2 , 13 Although prognosis is generally poor with recurrence or metastasis, there are several factors affecting the surgical treatment’s effectiveness. The most important factor is tumor size and thus how soon the diagnosis is made.…”

Section: Discussionmentioning

confidence: 99%

Liver Metastasis From Intracranial Hemangiopericytoma 8 Years After Initial Resection: Case Report

Rahmlow

Kolagatla

Mattingly

et al. 2022

Journal of Investigative Medicine High Impact Case Reports

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Solitary fibrous tumor/hemangiopericytoma (SFT/HPC) is a rare intracranial tumor that arises from pericytes surrounding the blood vessels. Solitary fibrous tumor/hemangiopericytoma accounts for less than 1% of primary brain tumors and is classified as grades I, II, or III based on mitotic count. These tumors often masquerade as meningiomas. Histologically, SFT/HPC is vascular with high cellularity and often surrounded by connective tissue. Immunohistochemistry is positive for stat 6, vimentin, and CD34. Although aggressive surgical resection is the mainstay of treatment, close long-term follow-up is necessary as recurrence or extra cranial metastasis can present several years after resection.

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“…The IHPC is an aggressive tumor with tendency for early loco regional recurrence and metastasis for different organs, including bone (19.6%), lungs and pleura (18.4%), liver (17.6%) and spine (14.1%). The intracranial tumor is rare and representes only 0.4% to 1% of all primary brain tumors, with only 10% being detected on the pediatric ages [8,11,12].…”

Section: Discussionmentioning

confidence: 99%

“…Because of the high recurrence rate and the tumor gravity, aggressive and careful therapies should be proceeded, and a long term follow up should be done, for at least 2, 5 years, in order to avoid extracranial metastases. Most cases of extracranial metastases are underestimated in number, because the adequate screening is not commonly done on asymptomatic patients after surgical approach [19,20,21].…”

Section: Discussionmentioning

confidence: 99%

Management of Patients with Hemangiopericytoma: Case Report and Literature Review

Cardoso¹

2019

AJHR

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The hemangiopericytomas (HPCs) are rare tumors of the dural base and correspond of less than 1% of all primary Central Nervous System (CNS) tumors. It usually affects adult males with 40 to 50 years old and has a supratentorial location (70%), followed by posterior fossa (15%) and spine (15%). Generally, it has fast progression and manifests clinically through headache, focal neurological deficits and epileptic seizures. The tumor has high incidence of local recurrence, from 34% to 90%, and it is estimated that the follow-up of these patients should be done for at least 7, 5 years. The percentage of longdistance metastases is lower, 12% to 55%, affecting especially bones, lungs and liver, in decreasing order. The objective of this study is to evaluate the contradictions when approaching these tumors and to analyze a rare case of pediatric involvement. It was prepared a case report and a literature review was made using the data bases MEDLINE®, PubMed and Cochrane, where 31 relevant articles were selected related to the proposed study. The outcome of HPC treatment can change according to the tumor's location in the CNS or extracranial, the tumor's size and the histopathological classification. Therefore, many studies have been proposed observing the answer of the surgical resection, the adjuvant radiotherapy, the radiosurgery and the antiangiogenic therapies.

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A Case Report of Meningeal Hemangiopericytoma: A 9-Year Journey from the Brain to the Spine

Cited by 6 publications

References 9 publications

Intracranial solitary fibrous tumor with delayed symptomatic metastasis to the lumbar spine: illustrative case

Intracranial solitary fibrous tumor with delayed symptomatic metastasis to the lumbar spine: illustrative case

Liver Metastasis From Intracranial Hemangiopericytoma 8 Years After Initial Resection: Case Report

Management of Patients with Hemangiopericytoma: Case Report and Literature Review

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