A case report of inflammatory myofibroblastic tumor of cecum mimicking malignant wall thickening

Inflammatory myofibroblastic tumor of the cecum presenting as acute abdomen, a rare pathology with a rarer presentation

“…These tumors show positivity for smooth muscle actin and can be positive or negative for other myoids (desmin, transgelin, etc.) [ 1 , 2 , 8 ], as it was found in our patient.…”

“…Recurrence appears in up to 5% of all cases and is associated with abdominopelvic location, tumor size beyond 8 cm, and older patients [ 1 , 2 , 8 ]. Surgical resection with negative margins is the only treatment that can offer a complete cure; in cases where the tumor cannot be resected because of its location or because of the invasion of vital organs, antihumoral drug therapy such as tyrosine kinase inhibitors (crizotinib, etc.)…”

Huge mesenteric inflammatory myofibroblastic tumor as a rare cause of intussusception with recurrence after 10 months: Case report and literature review

“…These tumors can arise in various areas such as the abdomen (including the retroperitoneum and pelvis), head/neck, upper respiratory tract, trunk, extremities, and uterus [ 3 ]. They encompass a range of fibroinflammatory conditions, characterized by a diverse arrangement of inflammatory cells and spindle cells [ 4 ].…”

“…However, typical symptoms are absent, but an accompanying inflammatory syndrome might manifest, which could include symptoms like fever, weight loss, anemia, elevated platelet count, polyclonal hypergammaglobulinemia, and an increased sedimentation rate. and a definitive diagnosis of IMT is confirmed through pathological analysis [ 1 , 4 , 5 ]. Surgery is the preferred approach for treatment, with complete removal along with clear margins offering the lowest likelihood of recurrence [ 4 ].…”

“…and a definitive diagnosis of IMT is confirmed through pathological analysis [ 1 , 4 , 5 ]. Surgery is the preferred approach for treatment, with complete removal along with clear margins offering the lowest likelihood of recurrence [ 4 ]. Currently, there is no substantiated basis to recommend the routine utilization of chemoradiation.…”