A Case Report of Cholangiocarcinoma Arising from a Biliary Adenofibroma: Radiologic Findings and Review of Literature

Abstract

Biliary adenofibromas are rare biliary epithelial tumors that are classified as benign. Nevertheless, some cases have been reported to show malignant transformations. The radiologic findings of biliary adenofibromas and their malignant transformation are not well-established because of their rarity. We present a case of a cholangiocarcinoma arising from a biliary adenofibroma assessed using ultrasonography, CT, and MRI. The differential diagnoses include other hepatic tumors.

Multimodal imaging findings of intrahepatic cholangiocarcinoma arising from a biliary adenofibroma: a case report with radiological–pathological correlation

“…On ultrasound, two cases presented as a hypoechoic mass [ 2 , 23 ], while the other four cases were mostly a hyperechoic mass [ 3 , 4 , 19 , 20 ]. In the present case, the portion of biliary adenofibroma showed high echogenicity with a clear boundary and the portion of cholangiocarcinoma showed low echogenicity with an irregular margin.…”

“…However, because of its rarity, detailed imaging characteristics of biliary adenofibroma and its malignant component have not been fully clarified. Indeed, for the malignant component, there were few reports with images available (2 cases with ultrasound [ 3 , 4 ], 8 cases with CT [ 2 – 9 ], 5 cases with MRI [ 3 , 4 , 10 , 11 ]). Here, we present the case of a 64-year-old woman who underwent surgery for a hepatic mass that was pathologically diagnosed as cholangiocarcinoma arising from biliary adenofibroma.…”