A Case Report of Cervical Embroynal Rhabdomyosarcoma Treated with Multimodality Approach

Abstract

Embryonal rhabdomyosarcoma of the female genital tract is a rare and highly malignant entity. It is usually diagnosed in adolescence, in contrast to vaginal rhabdomyosarcoma, which occurs mostly in infants. With the advent of multimodality treatment, prognosis seems to be improved. We report a case of a 20-year old young female presenting with a protruding mass from vaginal introitus and irregular bleeding. Polypectomy was done and microscopic findings were confirmed as a cervical embryonalrms.Neoadjuvant chemotherapy showed excellent response, after which Total Abdominal Hysterectomy and bilateral Lymphadenectomy was done. Histopathology showed embroyonalrhabdomyosarcoma involving cervical lip, infiltrating more than half thickness of cervical wall.Patient was treated with post-operative radiotherapy and she is on regular follow-up. The presence of a cervical polyp in an adolescent is a gynecological oddity and should be histologically examined. The prognosis of the cervical embryonal RMS depends on clinical and histological features. The current treatment protocols are based on trials.Patients with unfavorableprognosis characteristics, the multimodality approach including surgery, adjuvant chemo and radiotherapy can be effective. Otherwise, surgery alone can be effectively proposed.