A Case Report of Acute Acalculous Cholecystitis and Acute Hemorrhagic Cystitis due to Salmonella Typhi

Abstract

Acute acalculous cholecystitis and acute hemorrhagic cystitis due to Salmonella Typhi are a rare condition. A 24-year-old female patient was admitted to our clinic with abdominal pain, nausea, fever, headache, urinary burning, and bloody urine. Based on clinical, laboratory, and radiological evaluations, the patient was diagnosed with acute acalculous cholecystitis and acute hemorrhagic cystitis due to Salmonella Typhi. The patient was treated with intravenous ceftriaxone for two weeks. After the treatment, the patient's clinical and laboratory findings improved. Acute acalculous cholecystitis due to Salmonella Typhi concomitant with acute hemorrhagic cystitis is very rare and might be difficult to diagnose. Infectious agents such as Salmonella Typhi should be considered when acute acalculous cholecystitis and acute hemorrhagic cystitis are detected in adult patients with no underlying diseases.

Urocystitis and Ureteritis in Holstein Calves with Septicaemia Caused by Salmonella enterica Serotype Dublin

“…Urocystitis and urinary tract infection (UTI) caused by S. enterica subsp. enterica has been described in man (Tena et al, 2007;Na et al, 2013;Polat et al, 2014); however, descriptions in cattle are lacking. This work describes lower urinary tract lesions in four Holstein calves with septicaemia caused by S. Dublin.…”

“…It has been associated with old age, concomitant diseases such as diabetes mellitus, urolithiasis, urinary tract malformations, chronic disease or immunosuppressive therapy (Tena et al, 2007). Salmonella Enteritidis and S. Typhimurium are the serotypes most frequently isolated from people with UTI (Tena et al, 2007), although other non-typhoidal salmonellas and Salmonella Typhi have been implicated in cases of haemorrhagic cystitis (Na et al, 2013;Polat et al, 2014). Because people act as reservoirs only for S. Typhi and Salmonella Paratyphi, the occurrence of disease associated with non-typhoidal salmonellas suggests acquisition either from animal reservoirs or from contaminated animal products or foods (Na et al, 2013), so non-typhoidal salmonellosis is of great public health importance.…”

Chemoproteomic Profiling Reveals the Mechanism of Bile Acid Tolerance in Bacteria

“…Despite the high concentration of BAs, some bacterial pathogens can still survive from the BA stress and spread to other organs causing infection. For example, Salmonellae typhimurium and Escherichia coli can invade the gall bladder and tolerate high concentrations of BAs, leading to acute cholecystitis. , Several studies have investigated the mechanisms of bacterial BA tolerance. First, lipopolysaccharides (LPS) on bacterial outer membranes can prevent BAs from entering bacteria, and in particular, O-antigen is an important part in bacterial cell envelopes which functions to block the entrance of BAs .…”