A case report of acute kidney injury following the use of herbal vaginal pessary

Adejumo, Oluseyi Ademola; Akinbodewa, Akinwumi Ayodeji; Ogunleye, A.; Agoi, Oluwaseun Festus; Abolarin, Olatunji Sunday

doi:10.4103/2384-5589.209485

Cited by 4 publications

(2 citation statements)

References 1 publication

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“…This agrees with the findings of some other researchers [22,25]. Adejumo et al reported a case of acute kidney injury following the use of herbal vaginal pessary in a 22 year old female client [26]. Potential toxicities of herbal drugs are unknown to many people.…”

Section: Histological Changessupporting

confidence: 91%

Kidney-Induced Injury from Native Herbal Drugs: A Case Study of Certain Herbs Used in the Management of Infertility in Calabar, Nigeria

Ogar,

Itam

2024

IJPHPP

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Infertility is a global concern among married couples. Severally treatment approaches have been used over the years to proffer solution. This research aims at investigating the kidney–induced injury from native herbal drugs-case study of certain herbs used in the management of infertility in Calabar. A total of 18 Wistar rats weighing 150 - 250 grams were separated into 3 groups of 6 rats each and 2 groups were administered with 200 mg/kg each of ethanol and n-hexane combined extracts for 7 days. Results showed that ethanol and n-hexane extracts groups significantly affected the renal tissues of the experimental animals. While in control group, a section of the kidney showed normal findings of glomeruli and renal tubules. The ethanol extract group showed swollen glomeruli with deeply stained mesangial cells while the n-hexane extract group showed the glomeruli had a hypocellular mesangium causing a peri-arteriolar mesangial haemorrhage. Ethanol extract group and n-hexane extract group showed injury to the renal tissues on histology.

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Section: Histological Changessupporting

confidence: 91%

Kidney-Induced Injury from Native Herbal Drugs: A Case Study of Certain Herbs Used in the Management of Infertility in Calabar, Nigeria

Ogar,

Itam

2024

IJPHPP

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“…Considering the raising concerns on the traditional formulations for containing heavy metals, it becomes essential to understand in which form the heavy metal is present in the formulation. [6][7][8] This will help in understanding the possible nature of metabolism. Considering this, an attempt has been made to explore the structure and composition of Tamra bhasma through sophisticated instrumental facilities like thermo gravimetric analysis (TGA), X-ray diffraction (XRD), inductive coupled plasma with atomic emission spectroscopy (ICP-AES), scanning electron microscope coupled with wavelength dispersive spectroscopy (SEM-WDS) and particle size analyzer.…”

Section: Introductionmentioning

confidence: 99%

Analytical Specifications of Tamra Bhasma

Chaudhari¹

2018

Journal of Drug Research in Ayurvedic Sciences

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Introduction: In Ayurveda, metals and minerals are converted into biocompatible forms through specified classical procedures like Shodhana, Marana, etc. before their therapeutic use. Their frequent use without any noticeable side effects since ages is the ultimate proof of safety. But, safety and toxicity concerns are being raised by conventional researchers considering the presence of heavy metals in them. Noncompliance of pharmaceutical procedures as described in Ayurvedic classics is one possible cause for toxicity. At the same time, no standard analytical profiles are available for many metallic preparations. Materials and methods:The present study aims to prepare and develop preliminary analytical profiles for Tamra bhasma (calcined copper) with and without Amritikarana on structural and elemental basis to address the role of the raw materials used during the preparation, compound form, nature and particle size of both samples. Results and conclusion:The study revealed that Tamra Bhasma contains copper in a nano-crystalline structure having standard mean diameter ~12.72 μ in Tamra bhasma without Amritikarana and ~8.83 μ in Amritikarana sample. Copper sulfide form (CuS) associated with elemental sulfur was found to be a structural component in both samples.

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Use of Medicinal Plants in Africa: A Case Study From the Democratic Republic of Congo (DRC)

Zinga

Taba

Mesia

et al. 2022

Seminars in Nephrology

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A case report of acute kidney injury following the use of herbal vaginal pessary

Cited by 4 publications

References 1 publication

Kidney-Induced Injury from Native Herbal Drugs: A Case Study of Certain Herbs Used in the Management of Infertility in Calabar, Nigeria

Kidney-Induced Injury from Native Herbal Drugs: A Case Study of Certain Herbs Used in the Management of Infertility in Calabar, Nigeria

Analytical Specifications of Tamra Bhasma

Use of Medicinal Plants in Africa: A Case Study From the Democratic Republic of Congo (DRC)

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