A case report-giant cell tumour of soft tissue with low malignant potential in right axilla: A case report

Abstract

Primary giant cell tumour of soft tissue [GCT-ST] is a rare entity that is considered the soft tissue equivalent of giant cell tumour of the bone. It most commonly arises in soft tissues of the trunk and extremities, with occurrence in the head and neck being extremely rare. They are composed of nodules of histiocytes in a vascular stroma, with multinucleated osteoclast-like giant cells positive for vimentin, smooth muscle actin [SMA], CD68 and Tarterate Resistant Acid Phosphatase [TRAP]. Giant cell tumour of soft tissue is a rare primary soft tissue tumour with low malignant potential.

Giant cell tumor of soft tissue: GCT arising from periosteum of tibia

“…They can appear as cystic masses on imaging and may be mistaken for organizing hematomas and hence histopathological evaluation is necessary to confirm the diagnosis. 4 , 5 It is considered to have a low malignant potential, 6 however it may carry a high metastasis and death rate as described in a few studies. 1 In our case the lesion was arising from the periosteum of tibia.…”