A case of uterine corpus cancer with definitive staging after laparoscopic surgery, and preliminary diagnosis based on endometrial cytology

Abstract

Endometrial cancer should be considered in women with inappropriate vaginal bleeding, menstrual abnormalities, or discolored vaginal discharge. We experienced a case without the above risk factors, in which a preliminary diagnosis was made with endometrial cytology. The case was of a 66-year-old woman, gravida 2 and para 2. She had no inappropriate vaginal bleeding, and transvaginal ultrasound examination showed a thin endometrium. However, endometrial cytology was positive. We performed laparoscopic hysterectomy and bilateral salpingo-oophorectomy based on a clinical diagnosis of Stage IA uterine corpus cancer. The postoperative pathologic diagnosis was stage IB Grade 2 endometrial adenocarcinoma. Therefore, the possibility of uterine corpus cancer must still be considered in cases without risk factors. And cytologic sampling should be considered an effective method for diagnosis of uterine corpus cancer because of its high sensitivity and specificity.