A case of unusual presentation of Takayasu′s arteritis

Das, Debabrata; Mondal, Kanchan Kumar; Ray, Biswarup; Chakrabarti, Asim

doi:10.4103/0301-4738.60090

Cited by 24 publications

(19 citation statements)

References 9 publications

(12 reference statements)

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“…The most common clinical features are significantly low blood pressure (BP) and weaker pulses in the upper extremities associated with coldness or numbness of the fingers [4,5].…”

Section: Discussionmentioning

confidence: 99%

“…TA has been reported from different parts of the world, but the prevalence is more in oriental countries like Japan, India, Korea and Thailand [3]. The etiopathogenesis of the arthritis is not known, but studies are being conducted regarding the immunological and genetic aspects of the disease [3,4]. In most of the cases, irregular thickening of the walls of the aorta and its branch vessels with intimal stenosis is seen.…”

Section: Introductionmentioning

confidence: 99%

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A Case Report on Takayasu’s Arteritis

Mohan

Lakshmi

2017

Int J Pharm Pharm Sci

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Takayasu's arteritis (TA) is a rare large-vessel vasculitis that affects large arteries, mainly the aorta and its branches. It is also called a pulseless disease because of diminished or absent pulses in the upper extremities of the patient. The coronary, pulmonary and renal arteries are also affected in the progression of the disease. The prevalence of the disease is more in Asian countries and it has unknown etiopathogenesis. Here we discuss a case of TA in a 15 y old girl who was admitted with moderate LV dysfunction. The diagnosis was carried out from the results of CT aortogram which showed stenosis of right common carotid, left subclavian, left vertebral artery, right renal artery and lower lobe pulmonary arteries and other clinical examinations. Treatment was initiated with methylprednisolone and cyclophosphamide along with symptomatic treatment. But the disease progressed with the development of complications like peripheral leg ulcers. The patient was initiated palliative care in view of altered sensorium and severe LV dysfunction, but the patient succumbed to a sudden cardiac arrest. Early identification and initiation of aggressive treatment can help in symptom-free survival.

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“…The most common clinical features are significantly low blood pressure (BP) and weaker pulses in the upper extremities associated with coldness or numbness of the fingers [4,5].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case Report on Takayasu’s Arteritis

Mohan

Lakshmi

2017

Int J Pharm Pharm Sci

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“…Occlusion of the retinal vessels is the other reason for ocular symptoms in TA. It is reported that the retinal vessel involvement is very rare presentation of the disease [4, 6]. Vasa vasorum supports the media and adventitia of the vessels.…”

Section: Discussionmentioning

confidence: 99%

“…The initial inflammation around the vasa vasorum is the main histopathological feature in TA, which causes vascular inflammation and intimal proliferation [4]. Retinal vessel involvement, branch retinal artery occlusion, central retinal artery occlusion (CRAO), and branch retinal vein occlusion were demonstrated in previous reports [4, 6–10]. Kaushik et al demonstrated branch retinal artery occlusion in a TA patient with left subclavian and common carotid artery occlusion [10].…”

Section: Discussionmentioning

confidence: 99%

Central Retinal Artery Occlusion in Takayasu’s Arteritis as the First Presentation of the Disease

Güçlü

Gürlü

Özal

et al. 2016

Case Reports in Ophthalmological Medicine

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Takayasu's arteritis (TA) is a chronic inflammatory granulomatous vasculitis which affects large and medium arterial vessels. The disease involves especially subclavian arteries and aortic branches but it can consist of any arteries. The major pathology is granulomatous panarteritis with intima proliferation and defects of the elastic lamina of the vessels. We present a case of central retinal artery occlusion in TA as the first presentation of the disease. To the best of our knowledge, the present case is the first case that demonstrates central retinal artery occlusion as an initial manifestation in TA. A 48-year-old woman was admitted to our clinic with the complaint of sudden and painless vision loss in her right eye for one day. Although retinal artery involvement is a very rare presentation in TA, it is important to recall TA particularly in young patients with retinal artery occlusion.

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“…El compromiso ocular en esta aortitis se debe a isquemia retiniana secundaria al compromiso de grandes arterias, es más raro el compromiso de arterias retinianas; típicamente se ha descrito retinopatía con dilatación de pequeños vasos, microaneurismas capilares y anastomosis (6). También se puede ver cambios retinianos compatibles con retinopatía hipertensiva que se ve en el caso de hipertensión secundario al compromiso de la arteria renal.…”

Section: Dr Héctor Sosa (Medicina Interna)unclassified