A Case of Typhoid Fever Presenting With Multiple Complications

Buzğan, Turan; Omer, Endashaw; Irmak, Hasan; Karsen, Hasan; Akdeniz, Hayrettin

doi:10.29333/ejgm/82494

Cited by 5 publications

References 12 publications

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Colonoscopic findings and management of patients with outbreak typhoid fever presenting with lower gastrointestinal bleeding

Shaikhani

Husein

Karbuli

et al. 2013

Indian J Gastroenterol

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Lower gastrointestinal bleeding (LGIB) along with intestinal perforation is a well-known complication of typhoid fever. Reports of colonoscopic appearance and intervention of typhoid perforation involve only few cases. This series reports the colonoscopic findings and the role of colonoscopic hemostatic interventions in controlling the bleeding ileocolonic lesions. During the typhoid fever outbreak in Sulaymaniyah City in Iraqi Kurdistan Region, we received 52 patients with LGIB manifesting as fresh bleeding per rectum or melena. We performed total colonoscopy with ileal intubation for all cases. The findings were recorded and endoscopic hemostatic intervention with adrenaline-saline injection and argon plasma coagulation was applied to actively bleeding lesion. These patients were young, 11-30 years of age, with female preponderance. Blood culture was positive in 50 %. Colonoscopic findings were mostly located in the ileocecal region, although other areas of the colon were involved in many cases. Twenty-four percent of the cases required endoscopic hemostatic intervention by adrenaline injection with argon plasma coagulation which was effective in all patients except one who died in spite of surgical intervention in addition of endoscopic hemostasis. Dual endoscopic hemostatic intervention can be a safe and effective management option for patients with LGIB due to typhoid fever.

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Colonoscopic findings and management of patients with outbreak typhoid fever presenting with lower gastrointestinal bleeding

Shaikhani

Husein

Karbuli

et al. 2013

Indian J Gastroenterol

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Shanghai fever: A fatal form of Pseudomonas aeruginosa enteric disease

et al. 2015

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Salmonella Typhi–Induced Septic Shock and Acute Respiratory Distress Syndrome in a Previously Healthy Teenage Patient Treated With High-Dose Dexamethasone

Ugas

Carroll

Kovar

et al. 2016

Journal of Investigative Medicine High Impact Case Reports

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Typhoid fever is commonly characterized by fever and abdominal pain. Rare complications include intestinal hemorrhage, bowel perforation, delirium, obtundation, and septic shock. Herein we describe the case of a previously healthy 16-year-old male without history of travel, diagnosed with typhoid fever complicated by septic shock and acute respiratory distress syndrome treated with high-dose dexamethasone. This case details severe complications of typhoid fever that are uncommonly seen in developed countries, and the successful response to high-dose dexamethasone as adjunct therapy. High-dose dexamethasone treatment has reportedly decreased Salmonella Typhi mortality, but controlled studies specifically performed in children are lacking, and most reports of its use are over 30 years old and all have originated in developing countries. Providers should include Salmonella Typhi in the differential diagnosis of the pediatric patient with fever, severe abdominal pain, and enteritis, and be aware of its potentially severe complications and the limited data on safety and efficacy of adjunctive therapies that can be considered in addition to antibiotics.

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A Case of Typhoid Fever Presenting With Multiple Complications

Cited by 5 publications

References 12 publications

Colonoscopic findings and management of patients with outbreak typhoid fever presenting with lower gastrointestinal bleeding

Colonoscopic findings and management of patients with outbreak typhoid fever presenting with lower gastrointestinal bleeding

Shanghai fever: A fatal form of Pseudomonas aeruginosa enteric disease

Salmonella Typhi–Induced Septic Shock and Acute Respiratory Distress Syndrome in a Previously Healthy Teenage Patient Treated With High-Dose Dexamethasone

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