A Case of Trichilemmal Carcinoma With Distant Metastases in a Kidney Transplantation Patient

Hiramatsu, Kosuke; Sasaki, Kazunari; Matsuda, Masamichi; Hashimoto, Masaji; Tomikawa, Shinji; Fujii, Takeshi; Watanabe, Goro

doi:10.1016/j.transproceed.2014.10.015

Cited by 16 publications

(16 citation statements)

References 14 publications

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“…A case report of a kidney transplant recipient on immunosuppression, described by Hiramatsu22, brought the relationship between immunosuppression and a higher risk of cancer to the fore; of note is that this patient specifically developed an aggressive form of TC with subsequent metastatic spread. In the aforementioned study, resultant clear margins were obtained; however, the patient presented a year later with nodal spread, which was further complicated by liver and lung metastases 5 months after that.…”

Section: Discussionmentioning

confidence: 97%

Metastatic trichilemmal carcinoma in a patient with breast cancer

2016

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Trichilemmal carcinoma (TC) is described as a very rare cancer of the skin adnexa. Ninety per cent of the lesions present on the scalp. Prognostic factors in TC are limited to lymph node status and surgical margins, with no statistical significance observed for age or gender of the patient, size of tumour or locoregional recurrence. We present a 46-year-old black patient who developed TC during treatment for breast cancer. Postoperative histology of the scalp lesion excision confirmed no involved margins. At the three monthly appointment, the patient was reviewed and multiple, new scalp lesions were noted. A CT scan of the head, neck found multiple lesions on the scalp, limited to the soft tissue, not involving the outer table of the skull. There was bilateral invasion of the parotid glands. To the best of our knowledge, no syndromes or associations between breast cancer and adnexal skin tumours exist.

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Section: Discussionmentioning

confidence: 97%

Metastatic trichilemmal carcinoma in a patient with breast cancer

2016

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“…This rare malignancy arises as a solitary lesion on the head and neck of elderly patients, with no distinctive clinical features. Local recurrence after surgery and rarely metastatic disease has been reported …”

Section: Trichilemmal Groupmentioning

confidence: 99%

“…Local recurrence after surgery and rarely metastatic disease has been reported. 65,66 Histologically, like TL, a lobular growth pattern is common and the lesion exhibits a pushing, rather than frankly infiltrative border. 15 Cytological atypia is often marked, with numerous mitotic figures including abnormal forms.…”

Section: Trichilemmal Hornmentioning

confidence: 99%

Folliculosebaceous neoplasms: A review of clinical and histological features

Bhawan

2017

The Journal of Dermatology

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Numerous benign and occasionally malignant tumors arise from the folliculosebaceous apparatus. Confusing terminology, rarity of malignant variants and overlapping histological features can lead to diagnostic uncertainty. This review highlights the clinical and histopathological features that help to classify these entities, as well as the various syndromes associated with certain members of this large family of tumors.

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“…It develops from the hair follicle's external sheath [6]. It is usually indolent with a low metastatic potential although there have been reports of metastatic disease [6,7].…”

Section: Introductionmentioning

confidence: 99%

“…There have been two prior cases of trichilemmal carcinomas documented in kidney transplant recipient (KTR)s [7,8].…”

Section: Introductionmentioning

confidence: 99%

A kidney transplant recipient with recurrent trichilemmal carcinoma and multiple other primary malignancies

Grossberg

Diana

2020

AJN

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Kidney transplant recipients are at increased risk of developing malignancy, with prolonged immunosuppressive therapy being a strong risk factor. Non-melanoma skin cancers are most commonly reported and multiple primary malignancies are also described. This is the first report of a recurrent trichilemmal carcinoma, a rare cutaneous tumour, in a kidney transplant recipient. This case, and the associated literature, indicate that regular screening, thorough examination, and tailored immunosuppressive regimens are critical in managing these patients.

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A Case of Trichilemmal Carcinoma With Distant Metastases in a Kidney Transplantation Patient

Cited by 16 publications

References 14 publications

Metastatic trichilemmal carcinoma in a patient with breast cancer

Metastatic trichilemmal carcinoma in a patient with breast cancer

Folliculosebaceous neoplasms: A review of clinical and histological features

A kidney transplant recipient with recurrent trichilemmal carcinoma and multiple other primary malignancies

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