A case of synchronous bilateral spermatocytic seminoma

Leocádio, Dean E.; Stein, Barry S.

doi:10.1016/j.urolonc.2007.02.009

Cited by 7 publications

(5 citation statements)

References 8 publications

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“…However, 43 of these studies were excluded based on the inclusion and exclusion criteria. The remaining 51 studies included 39 in English [6,8–45], nine in Spanish [46–55], and one in Italian [56]. These studies encompassed a total of 938 men.…”

Section: Resultsmentioning

confidence: 99%

Bilateral testicular germ cell tumours: a systematic review

Zéqui¹,

Costa²,

Santana³

et al. 2012

BJU International

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What's known on the subject? and What does the study add? Bilateral testicular germ cell tumours (BTGCTs) are rare neoplasms. Most previously published studies consist of case reports or small retrospective case series. Little is known about their epidemiological and clinicopathological characteristics. BTGCT corresponded to 1.82% of testicular tumours. Metachronous disease was about twice as frequent as synchronous disease. The primary tumour histology, chemotherapy use and the interval between metachronous tumours influenced the histology of the second tumour. Overall, synchronous tumours were associated with more advanced disease and presented less favourable survival rates than metachronous tumours. Testicular cancer is the most common tumour in young men. It is known that a second primary contralateral testis tumour may occur in up to 5% of men with a proior tumour. About 35% of these men present with synchronous tumours, and 65% present with metachronous tumours. However there is little data about bilateral testicular germ cell tumours (BTGCT) in the literature and the most published articles are case reports on a small series of men, which makes it difficult to draw conclusions about therapeutic strategies for the treatment of BTGCTs. In fact, current guidelines for the treatment of testicular cancer contain little information related to bilateral disease. Therefore, the aim of our study is to provide a broad overview of BTGCT and to update data focusing on incidence, pathological features, and clinical outcomes of men with BTGCTs. Thus, an extensive review containing 94 studies and more than 50,000 patients was conducted.

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Section: Resultsmentioning

confidence: 99%

Bilateral testicular germ cell tumours: a systematic review

Zéqui¹,

Costa²,

Santana³

et al. 2012

BJU International

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“…5,6,8 Most such cases are metachronous, but occasionally they are synchronous. [8][9][10] Unlike classical seminoma, SS is not related to a preexisting cryptorchidism, except for a single reported case in a 44-year-old man. 11 Serum markers such as hCG and AFP, when reported, have been invariably negative.…”

Section: Clinical Featuresmentioning

confidence: 99%

Review Article: Spermatocytic Seminoma: Review of the Literature and Description of a New Case of the Anaplastic Variant

et al. 2011

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The aims of this paper were to review the literature of Spermatocytic Seminoma (SS) updating its clinico-pathological features and to present a new case of the exceptionally rare variant of this tumor known as anaplastic which only five cases have been reported. Many studies have confirmed that SS is a distinct neoplasm both clinically and pathologically from classical Seminoma and it differs from the latter especially in regard to behavior, characterized by an almost complete inability to metastasize with only very few convincing examples described with metastatic behavior. There is general agreement that orchidectomy is sufficient therapy for SS and that surveillance following surgery is the preferred management option. Surprisingly, the presence of an anaplastic component does not seem to impact on this excellent prognosis. Very different is the case of sarcomatous transformation, for which further therapy after orchiectomy is advisable.

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“…The incidence of bilaterality, either synchronous or metachronous, is nearly 10% of cases [12]. To date, eight cases of bilateral SS have been reported, including one from India [13], four from Japan [14], and three from the USA [10,15,16]. We present the first case review of bilateral SS, including patient age, symptom duration, tumor size, treatment, and outcomes (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…In such settings, adjuvant chemotherapy and radiotherapy may be beneficial. In bilateral SS cases, one case underwent chemotherapy and two received radiotherapy after orchiectomy [14,15]. There was only one patient who received no intervention except surveillance.…”

Section: Discussionmentioning

confidence: 99%

A rare case of bilateral sequential spermatocytic seminoma

Tian

et al. 2013

World J Surg Onc

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Spermatocytic seminoma (SS) is a rare testicular neoplasm characterized by a palpable, painless, slowly enlarging mass in the testis. Even more rare is a synchronous bilateral presentation. Only eight cases of bilateral SS have been reported in the literature, of which three cases were present with synchronous testis enlargement, and five were sequential. Here, we report an additional case of synchronous bilateral SS and present a comprehensive relevant literature review concerning clinical features, histopathology, and treatment.

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A case of synchronous bilateral spermatocytic seminoma

Cited by 7 publications

References 8 publications

Bilateral testicular germ cell tumours: a systematic review

Bilateral testicular germ cell tumours: a systematic review

Review Article: Spermatocytic Seminoma: Review of the Literature and Description of a New Case of the Anaplastic Variant

A rare case of bilateral sequential spermatocytic seminoma

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