A case of successful conservative chemotherapy for intramural pregnancy

Katano, Kinue; Ikuta, Kenji; Matsubara, Hirokazu; Oya, Naoko; Nishio, Masami; Suzumori, Kaoru

doi:10.1016/s0015-0282(99)00330-1

Cited by 26 publications

(19 citation statements)

References 4 publications

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“…6,13,17 For medical treatment, methotrexate can be administered directly to the intramural pregnancy via laparoscopic or transvaginal route, or systemically. 14,16 Although systemic methotrexate treatment and surgery are accepted modalities for tubal pregnancies, they are less effective for intramural pregnancies. 18 Sonographic-guided local methotrexate injections into gestational sacs of intramural pregnancies have been suggested.…”

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confidence: 99%

Sonographic diagnosis and successful medical management of an intramural ectopic pregnancy

Ong

Chia

et al. 2010

J of Clinical Ultrasound

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confidence: 99%

Sonographic diagnosis and successful medical management of an intramural ectopic pregnancy

Ong

Chia

et al. 2010

J of Clinical Ultrasound

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“…16 Systemic methotrexate administration has also been suggested as an alternative method of treatment for intramural pregnancy embedded in a uterine scar. 17 Our experience supports systemic (or local) methotrexate administration followed by expectant management as a noninvasive therapy.…”

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confidence: 99%

Sonographic and MR findings in 2 cases of intramural pregnancy treated conservatively

Lee

et al. 2006

J of Clinical Ultrasound

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“…Numerous studies have reported the early diagnosis of intramural pregnancy based on transvaginal USG and/or MRI (2,7–10). Memtsa et al (2) suggested several sets of criteria for the ultrasonographic diagnosis of intramural pregnancy and proposed a simple classification system that is useful in clinical practice.…”

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confidence: 99%

Distinguishing between intramural pregnancy and choriocarcinoma: A case report

et al. 2017

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Intramural pregnancy is a rare type of ectopic pregnancy with an unclear etiology. It may be associated with uterine wall injury and/or abnormal uterine conditions, such as adenomyosis, in certain cases. In the present report, a case of intramural pregnancy associated with adenomyosis is discussed. The patient was 34 years old and presented with amenorrhea for 40 days. Ultrasonography and magnetic resonance imaging revealed a mixed echogenic mass located within the posterior wall of the uterine fundus with abundant blood flow. In addition, the patient's β-human chorionic gonadotropin levels were markedly elevated; however, these levels demonstrated a declining tendency. Clinically, it was difficult to distinguish the diagnosis of the case between intramural pregnancy and choriocarcinoma. Following initial treatment with methotrexate-based chemotherapy, a laparotomy was performed to confirm the diagnosis and excise the lesion. Pathological analysis confirmed a diagnosis of intramural pregnancy and adenomyosis within the uterine wall. The results of the present case report suggest that surgical intervention should be the first action performed when intramural pregnancy is suspected, in order to confirm the diagnosis and treat the disease.

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A case of successful conservative chemotherapy for intramural pregnancy

Cited by 26 publications

References 4 publications

Sonographic diagnosis and successful medical management of an intramural ectopic pregnancy

Sonographic diagnosis and successful medical management of an intramural ectopic pregnancy

Sonographic and MR findings in 2 cases of intramural pregnancy treated conservatively

Distinguishing between intramural pregnancy and choriocarcinoma: A case report

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