A Case of Septic Arthritis of the Wrist due to<i>Finegoldia magna</i>

Arsene, Camelia; Saste, Abhijit; Somiah, Manya; Mestrovich, Janee; Berger, Gregory

doi:10.1155/2014/793053

Cited by 2 publications

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“…Fifty percent concordance for cultivation and broad-range PCR was observed in Akram et al study [ 3 ]. The results of PCR and HRMA was positive only for one negative culture case, in which F. magna was detected which confirmed by 16 s rRNA gene sequencing [ 36 ].…”

Section: Discussionmentioning

confidence: 88%

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

et al. 2021

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Background Accurate and rapid identification of microorganisms causing periprosthetic joint infections (PJIs) are necessary for choosing an appropriate antibiotic therapy. Therefore, molecular techniques are suggested for diagnosis in suspected PJIs. The Broad-range PCR and High-Resolution Melt Analysis (HRMA) were evaluated for the identification of causative organisms of PJIs in this study. Results For 47 of 63 specimens, both the culture and broad-range PCR were positive. The culture was found to be able of organism’s detection in 74.6% (47/63) of patients. Of 47 positive cultures, 11 (23.4%) were polymicrobial and 36 (76.59%) were monomicrobial cultures, in which 34 (91.89%) cases were detected by HRM assay. The sensitivity, specificity of HRMA vs monomicrobial culture were 91.89, 93.75%, respectively. The sensitivity, specificity of total HRMA (mono + poly) vs culture were 82.92, 93.75%. Conclusions HRM assay coupled with broad-range PCR are effective screening, rapid, and relatively cost-effective methods for discrimination of PJIs especially in aiding culture method. Using computer programs such as the Matlab-2018b program for HRM data analysis is also valuable and helpful in diagnosis.

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Section: Discussionmentioning

confidence: 88%

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

et al. 2021

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“…Septic etiology in young adults appears not to be the first diagnostic hypothesis to which practitioners may think before when faced to patient with a painful wrist and fiver because rheumatic causes are far more frequent [7]. According to Dubost et al, staphylococci and streptococci Group B above are the main germs responsible of septic arthritis in the past three decades [8].…”

Section: Introductionmentioning

confidence: 99%

Wrist Septic Arthritis Due to <i>Streptococcus pneumoniae</i> Revealing a Selective Immunoglobulin G4 Subclass Deficiciency: A Case Report

Walla¹,

Abalo²,

Kolou³

2015

OJO

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The pneumococcal septic arthritis is uncommon in healthy adults. In most cases, it occurs in patients with immune deficiency. Its exceptional location at the wrist can maintain doubt with rheumatic causes which are more frequent. IgG4 deficiency found in this patient was the only cause that could be impugned. We report the case of a young woman of 46 years without any evident cause of immunodeficiency and any particular risk factor, managed for septic arthritis of the wrist due to Streptococcus pneumoniae. This case without any apparent risk factors demonstrates that pneumococcal infection in a more distant articulation of the ENT is still possible. Scan has been a very significant contribution in confirming the positive diagnosis that leads to surgical drainage. The approach of the systematic search for the gateway must be done. In the study of the patient's immune status, the realization of the protein profile could be interesting and then guide the practitioner in the decision to vaccinate the patient against Streptococcus pneumoniae if he was not. We recommend looking always for a cause of immunodeficiency including primary Ig defiencies even among adult.

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A Case of Septic Arthritis of the Wrist due toFinegoldia magna

Cited by 2 publications

References 13 publications

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

Wrist Septic Arthritis Due to <i>Streptococcus pneumoniae</i> Revealing a Selective Immunoglobulin G4 Subclass Deficiciency: A Case Report

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A Case of Septic Arthritis of the Wrist due toFinegoldia magna

Cited by 2 publications

References 13 publications

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections

Wrist Septic Arthritis Due to &lt;i&gt;Streptococcus pneumoniae&lt;/i&gt; Revealing a Selective Immunoglobulin G4 Subclass Deficiciency: A Case Report

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Wrist Septic Arthritis Due to <i>Streptococcus pneumoniae</i> Revealing a Selective Immunoglobulin G4 Subclass Deficiciency: A Case Report