A case of scleredema adultorum successfully treated with narrow-band ultraviolet B phototherapy

Yoshimura, Junko; Asano, Yoshihide; Takahashi, Takehiro; Uwajima, Yuta; Kagami, Shinji; Honda, Hiromi; Idezuki, Takeo; Igarashi, Atsuyuki; Sato, Shinichi

doi:10.3109/14397595.2013.875640

Cited by 10 publications

(7 citation statements)

References 28 publications

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“…Rodnan skin score, and ultrasonography images taken prior and after treatment This research also further highlights narrow-band UVB phototherapy is as effective as low-dose UVA1 with a significantly lower cost. A case report from Japan highlights similar effectiveness of NB-UVB for scleroderma [10]. A Brazilian retrospective investigation of 11 patients with localized scleroderma found that several kinds of phototherapy, including UVA, PUVA, and NB-UVB, had comparable effectiveness both in terms of clinical and ultrasound evaluation [11].…”

Section: Discussionmentioning

confidence: 99%

Narrow-band ultraviolet B as a treatment option in linear morphea

Wirya¹,

Suryawati²,

Wirya³

et al. 2022

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Introduction: Morphea, also known as localized scleroderma, is a condition characterized by fibrosis of the skin and underlying tissue. Linear morphea is an infrequent condition especially in adults. Treatment of morphea is challenging because of its recalcitrant nature. Therapeutic options include the use of phototherapy and systemic immunosuppressants with variable success. Phototherapy used in morphea also varies, with ultraviolet A1 (UVA1) being the most frequently used therapy; however, the availability of UVA1 is scarce and may increase the risk of skin cancer. Narrow-band ultraviolet B (NB-UVB) is much more readily available and presents a much lower risk of skin cancer. Case report: Here we report a 27-year-old adult male with linear morphea on his lower extremity treated using NB-UVB. The patient underwent twenty sessions of NB-UVB and showed remarkable response to therapy. Conclusions: This case report further highlights a treatment option for linear morphea using NB-UVB.

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Section: Discussionmentioning

confidence: 99%

Narrow-band ultraviolet B as a treatment option in linear morphea

Wirya¹,

Suryawati²,

Wirya³

et al. 2022

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“… If methotrexate fails or is contraindicated, based on a risk‐benefit approach, the following alternative treatments can be proposed: glucocorticoids (systemic or intralesional), cyclosporine, prostaglandin E1, intravenous immunoglobulin, high‐dose penicillin, factor XIII infusion, cyclophosphamide, narrow‐band UVB, radiotherapy, electron‐beam radiotherapy and extracorporeal photopheresis …”

Section: Scleredemamentioning

confidence: 99%

European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis

Knobler

Moinzadeh

Hunzelmann

et al. 2017

J Eur Acad Dermatol Venereol

119

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The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present guideline focuses on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. In addition, current strategies in the first- and advanced-line therapy of sclerosing skin diseases are addressed in detail. Part 2 of this guideline provides clinicians with an overview of the diagnosis and treatment of scleromyxedema, scleredema (of Buschke) and nephrogenic systemic sclerosis (nephrogenic fibrosing dermopathy).

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“…Two patients were treated successfully with UVB radiation. Another patient did not respond to UVB treatment but showed a marked improvement after psoralen and ultraviolet A (PUVA)bath therapy (33,39,40). The best results were seen after PUVA therapy, with 3 patients showing marked improvement in symptoms (24,33).…”

Section: Phototherapy (Puva Puva-bath Uvb Uva1)mentioning

confidence: 99%

Treatment of Scleroedema Adultorum Buschke: A Systematic Review

Miguel¹,

Schliemann²,

Elsner³

2018

Acta Derm Venerol

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Scleroedema adultorum Buschke is a rare skin disease, which can be divided into 3 subtypes: classic type, occurring after respiratory infections; a type lacking association with infections; and a type associated with diabetes. Scleroedema adultorum Buschke is characterized by thickening and tightening of the skin, which typically starts at the neck. In half of patients, spontaneous remission may occur. The aim of this systematic review is to summarize all reported treatments for scleroedema adultorum Buschke, based on articles from PubMed database, using the query "scleroedema adultorum Buschke treatment", English and German, published between 1970 and 2016 and documenting adequate treatments. The results are based mainly on individual case reports, small case series, and retrospective studies often reporting unsuccessful results. Treatment options include topical as well as systemic treatments, and physical modalities. There is a need for randomized controlled trials and studies on long-term outcomes after treatment.

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A case of scleredema adultorum successfully treated with narrow-band ultraviolet B phototherapy

Cited by 10 publications

References 28 publications

Narrow-band ultraviolet B as a treatment option in linear morphea

Narrow-band ultraviolet B as a treatment option in linear morphea

European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis

Treatment of Scleroedema Adultorum Buschke: A Systematic Review

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