A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline

Abstract

Sarcoidosis is a disease with an unknown cause that affects multiple organ systems and has a varied clinical presentation. Often, its symptomatology mimics other disease processes, such as lymphoma, tuberculosis, and amyloidosis. The reticuloendothelial involvement and typical B symptoms of weight loss, fatigue, night sweats, and lymphadenopathy can make sarcoidosis often easily confused with lymphoma. Sarcoidosis has a myriad of central nervous system (CNS) effects, which are often not recognized as symptoms of the disease. These neuropsychiatric symptoms can include, but are not limited to, cognitive decline, headaches, and personality changes. In this report, we discuss a case of a patient who presented with symptoms consistent with indolent lymphoma but was eventually diagnosed with sarcoidosis with extrapulmonary manifestations.

Mind the Pitfall: Solitary Nodular Fasciitis Mimicking Extra-Nodal Manifestation of Hodgkin Lymphoma on [18F]FDG PET/CT

“…Clear differentiation of nodular fasciitis from viable extranodal manifestation of malignant lymphoma appears to be challenging on [ 18 F]FDG PET/CT imaging [6][7][8][9]. In addition, there is a variety of other known benign diseases which could also mimic malign manifestations on [ 18 F]FDG PET/CT [10][11][12][13][14].…”