A case of reverse takotsubo cardiomyopathy caused by an eating disorder

Tagami, Travis; Mertens, Amy; Rothschild, Daniel; Chowdhury, Pertha S.

doi:10.1016/j.jccase.2016.10.015

Cited by 17 publications

(15 citation statements)

References 11 publications

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“…However, literature data are extremely few. To the best of our knowledge, there are only 13 case reports (Tables 2, 3) describing the occurrence of TTS in IBD patients [26][27][28][29][30][31][32][33][34][35][36][37][38]. Interestingly, the totality of reported TTS occurred in female IBD patients.…”

Section: Discussionmentioning

confidence: 99%

“…As well as for TTS patients [17,39], the prevalence of affective disorders is high among IBD patients, particularly among female [18]. Besides the well-known role played by excessive catecholamine release in triggering TTS [26], such as in pheochromocytoma [27], IBD patients, and particularly CD patients, could show disease-specific triggers.…”

Section: Discussionmentioning

confidence: 99%

“…Mengoni et al [25] emphasize the role of disease exacerbation with consequent activation of inflammatory patterns and microvascular dysfunction [29]. According to Zegdi et al [23] and to Tagami et al [26], depression and affective disorders could represent specific triggers [27,30]. Interestingly, 4 out of 9 CD patients presenting with TTS were on treatment with corticosteroids and 5 out of 9 were affected by active CD (Table 2).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Takotsubo Syndrome and Inflammatory Bowel Diseases: Does a Link Exist?

Mirijello

D’Errico

Curci

et al. 2019

Dig Dis

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Background: Takotsubo syndrome (TTS) is an acute cardiac dysfunction in the absence of viral causes or obstructive coronary disease completely reversible within 4-8 weeks. Inflammatory bowel diseases (IBD) are a group of diseases caused by the interaction between immune system, genetic, and environmental factors against intestinal mucosa. Both these syndromes are characterized by complex mechanisms involving endothelial dysfunction and affective disorders. Aim: To assess the possibility of an association between IBD and TTS. Methods: First, we present a case of TTS in a patient affected by active stenosing Crohn's disease. Articles in English language were collected from PubMed and Google Scholar databases with the search terms "takotsubo," "IBD," "crohn disease," "ulcerative colitis". Results: Both TTS and IBD show multiple common features: preference for female patients, recurrent course of disease, association with endothelial dysfunction, and affective disorders. Patients affected by IBD could show specific triggers for TTS, such as malabsorption, electrolytes disturbances, and affective disorders. Conclusions: Despite pathophysiological similarities between TTS and IBD in active phase, future studies are needed to confirm this apparently possible association and to assess the presence of a pathophysiological link between these diseases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Takotsubo Syndrome and Inflammatory Bowel Diseases: Does a Link Exist?

Mirijello

D’Errico

Curci

et al. 2019

Dig Dis

View full text Add to dashboard Cite

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“…RTC is much less frequently found compared to apical or classic TC. There have been some case reports demonstrating other types of TC with AN [3], but, to our knowledge, only one report has discussed RTC in an anorexic female patient [8]. In that report, the patient could recover from RTC and heart failure with only conservative therapy.…”

mentioning

confidence: 95%

Reverse Takotsubo Cardiomyopathy and Shock Supported by Continuous Hemodiafiltration in a Patient with Anorexia Nervosa

Beppu¹,

Yoshida²,

Katsuki³

et al. 2017

Med Case Rep

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“…In comparison to other patterns of TCC, r-TCC usually presents in a younger patient population with higher troponin levels, lower ejection fraction, and a paradoxically faster recovery [4]. The higher troponin levels are believed to be the result of a larger region of myocardial involvement in r-TTC in comparison to the apex alone [2].…”

Section: Introductionmentioning

confidence: 99%

A Case of Reverse Takotsubo Cardiomyopathy Incited by a Spinal Subdural Hematoma

Sanchez

Glener

Esplin

et al. 2019

Case Reports in Neurological Medicine

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Takotsubo cardiomyopathy is a rare syndrome of transient, reversible left ventricular systolic dysfunction. It mimics myocardial infarction clinically and includes elevated cardiac enzymes, but echocardiography reveals apical ballooning and basal hyperkinesis. Infrequently, midventricular or even reverse Takotsubo patterns have been described, involving ballooning of the basal heart without the characteristic ‘Takotsubo’ appearance. There are cases in the literature that support a connection between reverse Takotsubo cardiomyopathy (r-TTC) and neurological insults as inciting factors. We report a case of r-TTC in an otherwise healthy 23-year-old man presenting with back pain, urinary retention, bradycardia, and hypertension. Troponin levels and brain natriuretic peptide (BNP) were elevated, and echocardiogram revealed an ejection fraction (EF) of less than 20%. In addition, MRI demonstrated a spinal subdural hematoma from T1-S1 with no cord compression. Repeated echocardiogram demonstrated an EF of 20-25% with a reverse Takotsubo pattern of cardiomyopathy. With supportive care, his clinical picture improved with normalization of cardiac enzyme and BNP values. This case represents a r-TTC presenting as heart failure in a young, apparently healthy male likely incited by a spinal subdural hematoma. To our knowledge, it is the first of its kind reported.

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A case of reverse takotsubo cardiomyopathy caused by an eating disorder

Cited by 17 publications

References 11 publications

Takotsubo Syndrome and Inflammatory Bowel Diseases: Does a Link Exist?

Takotsubo Syndrome and Inflammatory Bowel Diseases: Does a Link Exist?

Reverse Takotsubo Cardiomyopathy and Shock Supported by Continuous Hemodiafiltration in a Patient with Anorexia Nervosa

A Case of Reverse Takotsubo Cardiomyopathy Incited by a Spinal Subdural Hematoma

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