A case of resection of hepatocellular carcinoma associated with primary biliary cirrhosis (PBC) who had prior infection with HBV

Clinical significance of hepatectomy for primary biliary cirrhosis patients with hepatocellular carcinoma: Report of a single center case series and review of the published work

“…The indication of operation in PBC patients with HCC was the same as that of viral hepatitis patients with HCC described elsewhere . To the best of our knowledge, there were 22 case reports of hepatectomy for HCC in PBC patients in the English‐language (14 cases) and Japanese studies (eight cases) that were published during the same period . The definition of HCC in PBC patients in the published work review was consistent with our definition.…”

“…5 To the best of our knowledge, there were 22 case reports of hepatectomy for HCC in PBC patients in the English-language (14 cases) and Japanese studies (eight cases) that were published during the same period. 3,4,[6][7][8][9][10][11][12][13][14][15][16][17][18][19] The definition of HCC in PBC patients in the published work review was consistent with our definition.…”

“…Although HCC was often seen in end‐stage PBC patients, the reported number of hepatectomies for HCC in PBC patients is still small because their impaired liver functions prohibit performing hepatectomies at the time of diagnosis. Furthermore, liver transplantation (LT) has been established for both PBC and HCC patients; therefore, an end‐stage PBC patient with HCC would become a reasonable candidate for transplantation if the patient met the current transplantation guidelines . Thus, the use of hepatectomy for these patients has become increasingly rare.…”

“…Furthermore, liver transplantation (LT) has been established for both PBC and HCC patients; therefore, an end-stage PBC patient with HCC would become a reasonable candidate for transplantation if the patient met the current transplantation guidelines. 3,4 Thus, the use of hepatectomy for these patients has become increasingly rare. However, LT is not as feasible as hepatectomy because of the disparity between patient demand and donor organ supply.…”