A Case of Recurrent Eruptive Pseudoangiomatosis That Responded Well to Pimecrolimus 1% Cream

Tan, Cheng; Zhu, Weiming; Zhong, Min

doi:10.1159/000182267

Cited by 7 publications

(4 citation statements)

References 13 publications

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“…Ten of these 26 patients were undergoing immunosuppressive treatment or were elderly and institutionalized (vs. none of our cases) 1,3–9 . However, similarly to our report, the recurrence of the lesions does not appear to be related to the immune status of the subjects 10,11 . This suggests that EPA may not be associated with compromised immune status.…”

Section: Discussionsupporting

confidence: 77%

Eruptive pseudo‐angiomatosis lesions are associated with intravascular neutrophils and do not harbour Epstein–Barr virus

Jin

Chang

Shin

et al. 2010

Acad Dermatol Venereol

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Section: Discussionsupporting

confidence: 77%

Eruptive pseudo‐angiomatosis lesions are associated with intravascular neutrophils and do not harbour Epstein–Barr virus

Jin

Chang

Shin

et al. 2010

Acad Dermatol Venereol

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“…Affections with EPA may follow variable seasonal variations with different reports from different parts of the world. In a study by Cheng et al, it mostly occurred during the summer season [3,7,8,18], and in a study by Chuh et al, it was in the spring and summer seasons [2,9,10]. In the present study, 51.2% of the cases occurred during spring and 25.6% during autumn.…”

Section: Discussionsupporting

confidence: 50%

Eruptive pseudoangiomatosis: An epidemiological and clinical study

Mancy¹,

Awad²,

Hafedh³

2023

Our Dermatol Online

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Background: Eruptive pseudoangiomatosis is an acute-onset illness presenting with a characteristic rash mainly on the exposed parts of the body. It is mostly symptomless and resolves spontaneously without sequels. Numerous agents are suspected to trigger the disease. Materials and Methods: Forty-five patients affected with eruptive pseudoangiomatosis were examined at the Dermatology and Venereology Department of Al-Ramadi Teaching Hospital during the period from January 1, 2018, to January 1, 2020. History taking and physical examination in addition to laboratory investigations were done for all patients. Results: Forty-five patients, 27 females and 18 males, were examined. Their mean age was fifteen years and the female-to-male ratio was 1.5:1. The younger age group was the most involved and a family history was detected in 5%. Prodromal symptoms were found in 63.8% and pruritus was a complaint in 35.5% of the patients. The extremities and face were the most affected and the disease was more common during the spring season. Conclusion: Eruptive pseudoangiomatosis is a spontaneously-resolving illness without complications, yet one must be aware of it and keep it in mind when facing a viral rash to avoid unnecessary investigations and treatments and to provide reassurance to the patient and their family. Key words: angioma; pseudoangioma; viral infection; pruritus; URTI

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“…Eruptive pseudoangiomatosis was more frequently seen among less active individuals such as the elderly or hospitalized patients, and in mass outbreaks 4,5 . Many case reports were seen from the Mediterranean area, 3 Far East Asia, 7–13 that is, from areas where C. pipiens mosquitoes and other insects were said to inhabit naturally 19 . It is therefore very likely that many of these EP cases were actually bite responses to C. pipiens mosquitoes and other insects.…”

Section: Discussionmentioning

confidence: 99%

“…Eruptive pseudoangiomatosis (EP) 1–8 is an entity defined by the following clinical features: (i) multiple millet‐sized asymptomatic erythematous spots with an anemic halo distributed on exposed skin; (ii) the anemic halo may not appear with the spots on the face; (iii) the spots do not coalesce, and in the case of affected adults, 3–8 (iv) systemic symptoms are absent; and (v) the eruption lasts for more than 1 week. This disease entity was first reported by Higuchi 9 in 1943 as erythema punctatum, and thereafter a series of reports from Japan were published 10–13 .…”

Section: Introductionmentioning

confidence: 99%

Two cases of eruptive pseudoangiomatosis induced by mosquito bites

Oka¹,

Ohtaki²,

Kasai³

et al. 2011

The Journal of Dermatology

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Eruptive pseudoangiomatosis is a skin eruption characterized by millet-sized erythema with an anemic halo appearing on exposed body areas. Insect bites, particularly mosquito bites, have been reported as one of the causes of eruptive pseudoangiomatosis. We experienced two cases of eruptive pseudoangiomatosis and the eruption was seen on the face and upper extremities of two women aged 48 and 77 years old. The two cases consented to be experimentally bitten by Culex pipiens mosquitoes and Aedes albopictus to determine if eruptive pseudoangiomatosis could be experimentally elicited by these mosquitoes. Our results showed that several minutes after a C. pipiens mosquito bite, an erythematous spot appeared on the bite site, followed by the formation of an anemic halo surrounding the erythema in 30 min; a successful reproduction of eruptive pseudoangiomatosis. The erythema lasted for more than a week and was not accompanied by any pruritus. With A. albopictus, we were able to reproduce a milder eruptive pseudoangiomatosis eruption: in case 1, a smaller erythematous spot with an ill-defined halo which disappeared within 1 week; and in case 2, an immediate response consisting of a wheal and erythema but not eruptive pseudoangiomatosis. We demonstrated that eruptive pseudoangiomatosis was the response manifested in individuals who normally did not demonstrate any immediate or delayed reaction to insect bites; and the typical eruptive pseudoangiomatosis eruption was elicited by C. pipiens mosquito bites. However, the mechanism resulting in the manifestation of eruptive pseudoangiomatosis is still unknown.

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A Case of Recurrent Eruptive Pseudoangiomatosis That Responded Well to Pimecrolimus 1% Cream

Cited by 7 publications

References 13 publications

Eruptive pseudo‐angiomatosis lesions are associated with intravascular neutrophils and do not harbour Epstein–Barr virus

Eruptive pseudo‐angiomatosis lesions are associated with intravascular neutrophils and do not harbour Epstein–Barr virus

Eruptive pseudoangiomatosis: An epidemiological and clinical study

Two cases of eruptive pseudoangiomatosis induced by mosquito bites

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