A case of recurrent constrictive pericarditis induced by pericardial substitution with an expanded polytetrafluoroethylene membrane

Constrictive pericarditis caused by pericardial substitution using expanded polytetrafluoroethylene

“…However, although extremely rare, a few cases of ePTFE membrane-induced constrictive pericarditis have been reported. 2,3 These cases required reoperation due to hemodynamic deterioration. Similar to the present case, previous reports (based on intraoperative and histopathological findings) have considered that the inflammatory response may cause the formation of a fibrous membrane over the epicardium and the adhesion between the ePTFE sheets and epicardium, which resulted in restricted cardiac motion.…”

“…Covering the heart with expanded polytetrafluoroethylene (ePTFE) membranes to prevent cardiac injury during repeat sternotomy is considered effective in patients undergoing cardiac surgery 1 . However, constrictive pericarditis (a rare complication requiring surgical intervention) associated with the ePTFE membrane has been reported 2,3 . Herein, we present a unique case of constrictive pericarditis resulting from the use of ePTFE membranes to cover the heart.…”

“…1 However, constrictive pericarditis (a rare complication requiring surgical intervention) associated with the ePTFE membrane has been reported. 2,3 Herein, we present a unique case of constrictive pericarditis resulting from the use of ePTFE membranes to cover the heart. Written informed consent was obtained from the patient to publish this report and accompanying images.…”

Promotion of right ventricular outflow tract reconstruction using a novel cardiac patch incorporated with hypoxia-pretreated urine-derived stem cells

“…Currently available commercial patches include biological and synthetic materials such as knitted polyethylene terephthalate, expanded polytetrafluoroethylene, glutaraldehyde-fixed bovine pericardium, etc. [ [4] , [5] , [6] , [7] ] The electrical conductivity and mechanical properties of such materials do not match with those of normal myocardium, which may lead to an increased risk for arrhythmia, heart failure, and even sudden cardiac death [ [8] , [9] , [10] , [11] , [12] ]. For pediatric patients, the lack of growth potential of such patches is also an important issue.…”

Prevention of postoperative intrapericardial adhesion by dextrin hydrogel

“…A layer of DHG on the surface of the tissue acts as a physical barrier against blood, clots, fibrin, or other tissues, thereby preventing intraperitoneal adhesion [14]. On the other hand, non-absorbable artificial materials seem ineffective in preventing or at times even worsen the inflammatory response and tissue adhesion [16,17]. The effect of DHG in preventing intrapericardial adhesion has not been reported yet.…”