A Case of Recurrent Bowel Perforation in a Patient with Churg-Strauss Syndrome

Lee, Chang Hoon; Song, Jeong‐Hoon; Jang, Sung Jo; Han, Yong Jae; Lee, Myeung Su

doi:10.4078/jkra.2010.17.3.326

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Previous studies on CSS patients in Korea are mostly case reports [9][10][11][12][13][14][15][16]. In 2000, two clinical reports were published: one on intravenous high-dose cyclophosphamide infusion in five patients who had neuropathy refractory to a high-dose steroid, and the other on the electrophysiological features of the peripheral neuropathy in 12 CSS patients [17,18].…”

Section: Introductionmentioning

confidence: 99%

Clinical Features And Prognostic Factors Of Churg-strauss Syndrome

Kim¹,

Song²,

Lee³

et al. 2012

Journal of Allergy and Clinical Immunology

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Section: Introductionmentioning

confidence: 99%

Clinical Features And Prognostic Factors Of Churg-strauss Syndrome

Kim¹,

Song²,

Lee³

et al. 2012

Journal of Allergy and Clinical Immunology

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Clinical features and prognostic factors of Churg-Strauss syndrome

Kim

Sohn

Song

et al. 2014

Korean J Intern Med

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Background/AimsChurg-Strauss syndrome (CSS) is a rare systemic necrotizing small-vessel vasculitis, with accompanying bronchial asthma, eosinophilia, and eosinophilic infiltration of various tissues. The purposes of our study were to characterize the clinical features of CSS and to identify factors associated with CSS prognosis in Koreans.MethodsMedical records were reviewed retrospectively for all physician-diagnosed CSS patients in the Seoul National University Hospital between January 1990 and March 2011.ResultsData from 52 CSS patients were analyzed. The respiratory tract was the most commonly involved organ (90.4%). Renal involvement was less frequent in antineutrophilic cytoplasmic antibody (ANCA)(-) patients than in ANCA(+) patients (p = 0.048). Clinical remission occurred in 95.3% of patients, but 16.3% of them relapsed. Patients who maintained remission for more than 6 months were relatively older (median, 51 years) at diagnosis (p = 0.004), had been diagnosed in earlier stages (p = 0.027), showed more frequent respiratory involvement (p = 0.024) and generalized symptoms (p = 0.039), and showed less frequent cutaneous involvement (p = 0.030) than those who did not achieve persistent (> 6 months) remission. Patients who achieved persistent remission also showed higher C-reactive protein (CRP) levels (p = 0.031) than those who did not.ConclusionsANCA(-) CSS patients showed less frequent renal involvement. Characteristics of good responders were older age, diagnosis at earlier stages, less cutaneous involvement, more respiratory involvement, high CRP values, and more generalized symptoms.

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A Case of Recurrent Bowel Perforation in a Patient with Churg-Strauss Syndrome

Cited by 2 publications

References 12 publications

Clinical Features And Prognostic Factors Of Churg-strauss Syndrome

Clinical Features And Prognostic Factors Of Churg-strauss Syndrome

Clinical features and prognostic factors of Churg-Strauss syndrome

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