A Case of Rectal Malakoplakia in an Immunocompromised Woman With Chronic Colonic Bacterial Infections

Berger, Scott; Marginean, Celia; Kaur, Manreet

doi:10.1016/j.cgh.2022.06.004

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At this moment, there is no therapy considered the gold standard for this rare disease. Therapeutic alternatives are: antibiotic therapy using agents that interact directly with the macrophages, like the quinolones or trimethoprim-sulfamethoxazole diminution or even suspension of the doses prescribed for the immunosuppressive therapy a good control of the associated immunosuppressive pathology endoscopic resections for the cases with localized lesions surgical resection for the cases that present multiple organ infiltration and or suspected malignancy [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ]. …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Surgical Challenge Generated by Colonic Malakoplakia in Disguise as a Locally Advanced Colonic Malignancy—A Case Report

Şerban

Toma²,

Voicu

et al. 2023

Medicina

View full text Add to dashboard Cite

Colonic malakoplakia is an uncommon granulomatous development of cells resulting from the impaired capacity of the mononuclear cells to eliminate the phagocytosed bacteria, and in rare cases it can also affect the gastrointestinal tract. We report the case of a 78-year-old female patient that was admitted to hospital by The Emergency Department with the diagnosis of bowel obstruction, confirmed by the clinical and paraclinical investigations. We decided to surgically manage the case for suspicious symptomatic colonic neoplasm. The histological examination of the surgical specimens revealed colonic malakoplakia, characterized by the presence of the aggregated granular histiocytes and Michaelis-Gutmann bodies. Through this paper, we want to raise awareness for Malakoplakia, which remains an extremely rare disease that may affect multiple organs, and because it does not present specific symptoms or clinical manifestations, the final diagnosis remains the histopathological study. The clinical conduct should be decided after taking into consideration all the aspects of this pathology along with the benefits and risks for the patient.

show abstract

Section: Discussionmentioning

confidence: 99%

“…surgical resection for the cases that present multiple organ infiltration and or suspected malignancy [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

A Surgical Challenge Generated by Colonic Malakoplakia in Disguise as a Locally Advanced Colonic Malignancy—A Case Report

Şerban

Toma²,

Voicu

et al. 2023

Medicina

View full text Add to dashboard Cite

show abstract

“…Yu-Chun Ma et al (2022) described a case of colonic malakoplakia with the peritoneal cavity and retroperitoneum extension mimicking advanced colonic malignancy [ 3 ]. Scott Berger et al (2022) reported a case of rectal malakoplakia in an immunocompromised woman with interstitial lung disease [ 4 ]. These studies indicate that malakoplakia more frequently develops in immunocompromised patients, with a higher preponderance in females.…”

Section: Introductionmentioning

confidence: 99%