A Case of Rare Small Bowel Tumor in a Child and Review of Literature

Deepak, J; Aravind, K L; Gowrishankar,; Ramesh, S

doi:10.1007/s13193-015-0417-9

Cited by 1 publication

(7 citation statements)

References 9 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Imaging usually demonstrates a hypoechoic or hypoattenuating lesion which may be hypervascular with or without calcifications (Fig. 1) (1,2,4,6,8,10,12,13). When found endoscopically appearances are typically sessile and polypoid (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have suggested that these lesions may result from disordered inflammation. Postulated triggers include infections, previous surgery, inflammatory and autoimmune conditions, however the only relevant contributing past medical history was found in two patients with Wilms tumour and H pylori gastritis (8,13).…”

Section: Discussionmentioning

confidence: 99%

“…Inflammatory myofibroblastic tumours are locally invasive and have a high local recurrence rate (15-40%) (5,8). Presentations are variable but classically inflammatory symptoms (fever, night sweats and elevated inflammatory markers) and symptoms secondary to local mass effect are observed.…”

mentioning

confidence: 99%

“…Tumour histology consists of sheets or entwining bundles of ganglion-like/spindled polygonal cells interspersed with areas of myxoid change with an inflammatory infiltrate of plasma cells, eosinophils and lymphocytes in a loose stroma with variable degrees of fibrosis and collagen deposition (Fig. 1) (8)(9)(10). Management is total resection where possible though successful medical management is described.…”

mentioning

confidence: 99%

“…Pancreatic lesions are the rarest gastroenterological site with 14 reported paediatric cases (5)(6)(7). These lesions may result from disordered inflammation with postulated triggers including infections, previous surgery, inflammatory and autoimmune conditions (6,8).…”

mentioning

confidence: 99%

See 4 more Smart Citations

Paediatric Gastrointestinal, Hepatic and Pancreatic Inflammatory Myofibroblastic Tumours, A Single Centre Experience

Couper

Eldredge

Kirby

et al. 2021

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

Inflammatory myofibroblastic tumours (IMTs) are rare soft tissue tumours. Reports of gastrointestinal tract, liver and pancreas tumours are limited. The objective of this study is to identify presenting features, contributing prognostic / etiological factors and any variability in outcomes in the context of different historical treatments. We retrospectively reviewed the records of seven children treated at our hospital between 2006 and 2019 and assessed the demographic, presentation, treatment, immunohistochemistry, and outcomes of their tumours. Age range at presentation was 4 months-15 years with a male predominance. Presentations were typically due to local mass effect or incidental discovery. Systemic symptoms were rare. Outcomes were good with six out of seven stable or in remission irrespective of treatment. Surgical resection where possible is the treatment of choice. Medical therapy had good outcomes with chemotherapy acting as first line treatment when required. The only negative prognostic factor identified was local spread at the time of presentation.

show abstract