2013
DOI: 10.3748/wjg.v19.i32.5385
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A case of rapidly progressing leiomyosarcoma combined with squamous cell carcinoma in the esophagus

Abstract: Esophageal leiomyosarcoma is a rare tumor that accounts for less than 1% of all malignant esophageal tumors. Esophageal leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary leiomyosarcoma. We experienced a case of leiomyosarcoma combined with squamous cell carcinoma that progressed very rapidly.

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Cited by 3 publications
(6 citation statements)
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“…It is estimated that esophageal LMS accounts for about 0.5% of esophageal carcinomas [ 3 ]. Esophageal LMS concurrent with carcinoma is even rarer [ 6 , 9 , 11 – 16 ]. The summary of such cases is presented in Table 1 .…”
Section: Discussionmentioning
confidence: 99%
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“…It is estimated that esophageal LMS accounts for about 0.5% of esophageal carcinomas [ 3 ]. Esophageal LMS concurrent with carcinoma is even rarer [ 6 , 9 , 11 – 16 ]. The summary of such cases is presented in Table 1 .…”
Section: Discussionmentioning
confidence: 99%
“…To our knowledge, there are only eight cases of simultaneous LMS and SCC, of which three cases were in the esophagus [ 6 , 15 , 16 ]. In a study by Jang et al [ 6 ], a 72-year-old male patient presenting with chest pain was diagnosed with polypoid LMS in mid esophagus combined with SCC, similar to our case. However, the diagnostic method and tumor progression differed, as they reported a rapidly growing LMS, although LMS is generally considered a tumor with a slow growth rate [ 17 ].…”
Section: Discussionmentioning
confidence: 99%
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“…However, there were other possibilities in this case [ 11 ]. If it was a malignant submucosal tumor such as gastrointestinal stromal tumor (GIST) and leiomyosarcoma which might also present with low echoic aspect in EUS and increased FDG uptake in PET-CT [ 12 , 13 ], it must be resected surgically apart from lymphoma. We also supposed the tumor to be GCT, which was possible to remove endoscopically, because it was yellowish and low echoic, even if it was atypical due to the increased FDG uptake.…”
Section: Discussionmentioning
confidence: 99%