A Case of Pulmonary Sarcoidosis Misdiagnosed as Tuberculosis

Rana, Srijna; Kaur, Rajwinder; Kajal, Nirmal Chand; Ps, Nishanth

doi:10.4103/jacp.jacp_32_17

Cited by 3 publications

(3 citation statements)

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“…[ 23 ] It is common to treat Sarcoidosis with empirical antitubercular therapy until the correct diagnosis is made, leading to drug toxicity and often-acute hepatic failure. [ 24 ] The current study is aimed at differential diagnosis of PTB, Sarcoidosis and Healthy samples using microarray data, which provides differentially expressed genes based on signal intensity to build an Artificial Intelligence (AI) based model for diagnosing active disease with healthy control. The study comprises of blood mRNA transcriptional response of tuberculosis (TB) patients to study the host immune response using microarray profiling.…”

Section: Resultsmentioning

confidence: 99%

An ANN model for the differential diagnosis of tuberculosis and sarcoidosis

et al. 2020

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Section: Resultsmentioning

confidence: 99%

An ANN model for the differential diagnosis of tuberculosis and sarcoidosis

et al. 2020

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“…Tuberculosis often overlaps with sarcoidosis. [11][12][13] Agarwal et al and Gupta et al stated that tuberculous sarcoidosis: Is not a separate entity, and many a times a physician encounters situations wherein sarcoidosis may precede, follow or present concurrently with TB. 15,16 According to an official American thoracic society clinical practice guideline.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis presenting as Lofgran’s syndrome

Malik¹,

Sajjan²,

Shivkumar³

et al. 2020

Int J Res Med Sci

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A 40 year old male, first presented with erythema nodosum, fever, weight loss and joint pains and did not respond to anti-tubercular treatment. One year later he came back with joint pains, erythema nodosum, fever and dry cough. He also had weakness in distal right lower limb more than left limb. He had raised ESR, hypocalcaemia, raised ACE levels and lymphnode involvement on HRCT, with skin biopsy suggestive of sarcoidosis. This time patient responded to treatment and is on regular follow up.

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“…Sarcoidosis was another condition misdiagnosed as PTB in six patients. The clinicoradiological features of sarcoidosis are similar to TB, thus posing a great challenge in countries endemic for TB [21,22]. Pulmonary sarcoidosis, is often misdiagnosed as SN PTB.…”

Section: Casementioning

confidence: 99%

Smear Negative Pulmonary Tuberculosis Is a Distinct Clinical Entity, Not a "Misdiagnosis Waste Basket"

E¹,

O²,

A³

et al. 2022

Int J Respir Pulm Med

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Background: PTB can mimic many chronic lung diseases resulting in misdiagnosis with serious consequences. Objectives:To appraise all SN PTB patients who were referred to us from lower health facilities after unsuccessful treatment in order to confirm the appropriate diagnosis. Methods:A cross sectional study at the pulmonary section of our hospital. Results:The median age of our patients was 46 with interquartile range of 32 to 54 years. The commonest presenting symptom was difficulty in breathing which was present in almost 90% of them (30 out of 34), cough was present in 24 with sputum production in 22 while haemoptysis was reported in 3. All the 5 patients with malignancy reported chest pain. Sixty eight percent of the patients were referred from Peripheral TB DOT centers and sputum smear tests were done in 82% of them while radiologic tests were done in less than 50% of the patients. The final diagnoses include COPD, malignancy, sarcoidosis, interstitial lung diseases and fungal infection among others. Conclusion: Many lung diseases are misdiagnosed as SN PTB because of similarity in clinical presentation, overreliance on diagnostic test with low TB detection and non adherence to local guidelines. We advocate for WHO-recommended rapid molecular test for all our suspected TB cases and prompt referral of difficult to diagnose cases.

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A Case of Pulmonary Sarcoidosis Misdiagnosed as Tuberculosis

Cited by 3 publications

References 0 publications

An ANN model for the differential diagnosis of tuberculosis and sarcoidosis

An ANN model for the differential diagnosis of tuberculosis and sarcoidosis

Sarcoidosis presenting as Lofgran’s syndrome

Smear Negative Pulmonary Tuberculosis Is a Distinct Clinical Entity, Not a "Misdiagnosis Waste Basket"

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