A case of primary orbital melanoma treated by local excision.

Undifferentiated Sinonasal Carcinoma With Nasolacrimal Duct Obstruction

“…10 Relatively low-grade tumors, such as the one described here, may be managed fairly conservatively, without the need for total exenteration. 9 Mixed cell type and high mitotic count, 8 neither of which were found in this patient, were proposed as negative prognostic indicators.…”

Melanoma maligno primário da órbita

“…Series of primary orbital melanomas show ages varying between 12 and 84 years 3,5 . There are only two cases of African-descendant patients [3][4][5] .…”

“…Orbital primary melanomas are probably originated from the congenital remains of cells from the neural crest, and may be found along ciliary nerve, scleral emissary veins or the leptomeninx of the optical nerve [3][4][5][6] . Due to the small number of cases, there is not much data regarding its clinical behavior, however, the most common clinical presentation is pain-associated proptosis originated from a diffuse orbital mass4.…”

“…Radiotherapy and chemotherapy have been used as additional treatment, with uncertain results. [3][4][5] .…”

“…In the orbit, it is frequently secondary to invasions by conjunctiva, choroid melanomas or from adjacent regions, or blood-born metastases 3 . The primary orbital melanoma represents less than 1% of the primary orbital neoplasias 4 .…”