A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus

Hosaka, Shigetoshi; Nakamura, Naoshi; Akamatsu, Taiji; Fujisawa, Toru; Ogiwara, Yasuhiro; Kiyosawa, Kendo; Hidaka, Eiko; Ota, Hiroyoshi; Katsuyama, Tsutomu; Inagaki, Hiroshi

doi:10.1136/gut.51.2.281

Cited by 40 publications

(41 citation statements)

References 26 publications

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“…We report a case of primary esophageal B cell MALT lymphoma in an immune competent patient. Only a few other cases of this particular morphological type of primary esophageal lymphoma have been reported in literature [7,12] . Patients with acquired immunodeficiency syndrome (AIDS) are at an increased risk of developing malignant lymphomas, with the gastro intestinal tract being the most common site [13] .…”

Section: Discussionmentioning

confidence: 97%

“…[5] MALT lymphomas can arise in various anatomic locations where lymphocytes are usually absent due to acquisition of MALT, including the gut, lung, thyroid, salivary glands and liver [6] . Primary esophageal lymphoma is extremely rare [7] . Esophageal involvement by lymphoma is usually secondary to local spread from the stomach or the mediastinum [8] .…”

Section: Discussionmentioning

confidence: 99%

“…Esophageal involvement by lymphoma is usually secondary to local spread from the stomach or the mediastinum [8] . Very few cases of primary esophageal lymphomas were reported in literature [6][7][8][9][10][11] . There are many morphological variants with most of the common being large B cell type and Non-Hodgkin's lymphoma [9] .…”

Section: Discussionmentioning

confidence: 99%

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Extremely rare case of primary esophageal mucous associated lymphoid tissue lymphoma

Malik

Baig²,

Ahmed³

et al. 2013

WJGE

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SJ is a 37-year-old male who presented with one year history of dysphagia, odynophagia and 15 pounds weight loss. He underwent endoscopic evaluation which showed mid esophageal ulcers. It was thought that the cause of the ulcer was the multivitamins and the patient was asked to stop them. Furthermore Esomeprazole therapy was also initiated. Patient's symptoms persisted but he did not seek any medical attention until about one year later. Meanwhile the patient reported additional 15 pounds of weight loss. We repeated upper endoscopy again which showed evidence of two chronic non bleeding irregular friable ulcerations seen in the mid esophagus, 31 cm from the incisors. Biopsies and frozen section were taken and sent for assessment to the Pathology lab. Immunoperoxidase studies on frozen sections showed the presence of IgM and for most plasma cells IgG. The microscopic and histologic findings were consistent with mucous associated lymphoid tissue lymphoma with plasmocytic differentiation. Computed tomographic scan done showed no evidence of spread to adjacent structures. The patient was referred to oncology and several cycles of radiation and Rituximab therapy were initiated which cured the disease. Subsequent endoscopies with blind biopsies were done which were negative for any neoplastic process. Key words: Lymphoma; Mucous associated lymphoid tissue; EsophagusCore tip: This is a case of a 37-year-old gentleman presenting with chronic esophageal ulcers. Endoscopic biopsy samples were taken. Immunohistochemistry and hematoxylin and eosin staining of the biopsy samples were consistent with mucous associated lymphoid tissue (MALT) lymphoma. There was no sign of disease process in the stomach, and radiological studies revealed no evidence of metastasis. In consideration of these findings a diagnosis of primary esophageal MALT lymphoma was made, which is an extremely rare occurrence. On the basis of our experiences we recommend keeping primary esophageal MALT lymphoma in the differential diagnosis of chronic esophageal ulcers that are resistant to conservative management.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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Extremely rare case of primary esophageal mucous associated lymphoid tissue lymphoma

Malik

Baig²,

Ahmed³

et al. 2013

WJGE

View full text Add to dashboard Cite

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“…To date, there have been approximately twenty reported cases of primary esophageal lymphoma [6][7][8][9][10][11]. The majority of patients were older than 45 years of age and had mid-to lower-esophageal disease.…”

Section: Discussionmentioning

confidence: 99%

Primary esophageal CD30-positive ALK-positive anaplastic large cell lymphoma with MUM1 expression

et al. 2012

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We report a case of primary esophageal CD30 ? /ALK ? /MUM1 ? anaplastic large cell lymphoma (ALCL) and discuss its diagnosis and treatment, specifically in regard to the unusual expression of the B cell marker, MUM1. A 29-year-old Mexican male presented with an esophageal mass with stenosis and dysphagia. Endoscopic samples were sent for hematoxylin-eosin staining and immunohistochemical analysis. Pathologic and immunohistochemical examination resulted in a diagnosis of primary ALCL of the esophagus with CD30 ?

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“…L'association des LMNH à une infection par le VIH est retrouvée dans la littérature avec une incidence de 5 % en cas de sidamaladie [6]. L'aspect endoscopique est non spécifique, et c'est l'étude anatomopathologique associée à l'immunohistochimie et notamment par la positivité des marqueurs spécifiques (Ac anti-CD20) qui confirme le diagnostic [7]. Le scanner thoracoabdominopelvien recherche une localisation extraoesophagienne sus-et sous-diaphragmatique pour confirmer le caractère primitif de la lésion.…”

Section: Discussionunclassified

Lymphome malin non hodgkinien primitif de l’œsophage chez un patient immunocompétent

et al. 2011

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A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus

Cited by 40 publications

References 26 publications

Extremely rare case of primary esophageal mucous associated lymphoid tissue lymphoma

Extremely rare case of primary esophageal mucous associated lymphoid tissue lymphoma

Primary esophageal CD30-positive ALK-positive anaplastic large cell lymphoma with MUM1 expression

Lymphome malin non hodgkinien primitif de l’œsophage chez un patient immunocompétent

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