A Case of Primary Leiomyosarcoma of the Lesser Omentum

Sasamoto, Akitoshi; Yamaguchi, Akihiro; Isogai, Masatoshi; Hori, Akihiro; Kin, Yukoh; Kitagawa, Yuichi

doi:10.3919/jjsa.59.1409

Cited by 3 publications

(3 citation statements)

References 2 publications

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“…About half of all omental GISTs are misdiagnosed as extra mucosal tumors of the stomach. 41 , 42 , 44 Additionally, omental EGISTs seem to be morphologically and immunohistochemically identical to their gastric and intestinal counterparts. They are cellular tumors consisting of elongated spindle and epithelioid cells that are typically positive for c-kit (CD117) and, less consistently, for CD34.…”

Section: Discussionmentioning

confidence: 91%

Extra-Gastrointestinal Stromal Tumor of the Omentum: A Rare Case Report and Review of the Literature

Fagkrezos

Touloumis²,

Giannila

et al. 2012

Rare Tumors

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Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal spindle-cell or epithelioid neoplasms, located mainly with higher frequency in the stomach and small bowel. GISTs represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein a transmembrane tyrosine kinase receptor for stem cell factor. Extra-gastrointestinal stromal tumors tend to present In fewer than 5% of cases; they originate primarily from the mesentery, omentum or peritoneum. Furthermore, these extra-gastrointestinal tumors (EGIST) tend to be more common in patients over the age of 50 years. EGISTs are neoplasms with overlapping immunohistological features, occurring in the abdomen outside the gastrointestinal tract with no connection to the gastric or intestinal wall. We describe here a rare case of EGIST of the lesser omentum and report the clinical, macroscopic, immunohistological and radiological features of an EGIST arising in the lesser omentum of a 63-year old man. Clinical course and the prognostic factors of such lesions will also be discussed. EGISTs in the lesser omentum can grow slowly and remain silent despite a large tumor size. In most cases, a pre-operative diagnosis is not possible, and the patient undergoes a surgical operation for the generic diagnosis of abdominal mass. During the intervention it is important to achieve a complete removal of the mass and to examine every possible adhesion to the gastrointestinal wall.

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Section: Discussionmentioning

confidence: 91%

Extra-Gastrointestinal Stromal Tumor of the Omentum: A Rare Case Report and Review of the Literature

Fagkrezos

Touloumis²,

Giannila

et al. 2012

Rare Tumors

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“…In fact, about half of all omental GISTs are misdiagnosed as extramucosal tumors of the stomach. [8][9][10][11] Surgical resection is the only effective treatment as no adjuvant therapy has been established. 2 Furthermore, no postoperative recurrences of omental GISTs without myogenic or neurogenic features have been reported, 1,3 although 5 of the 10 patients with mesenteric GISTs lacking myogenic and neurogenic features had a poor outcome despite surgical resection.…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal Stromal Tumor of the Lesser Omentum: Report of a Case

Fukuda¹,

Suwa²,

Kimura³

et al. 2001

Surgery Today

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We describe herein an extremely unusual case of a gastrointestinal stromal tumor (GIST) of the lesser omentum. A 45-year-old man was admitted to our hospital with an intra-abdominal mass that was subsequently misdiagnosed as a submucosal tumor of the stomach. The tumor arose from the lesser omentum and was removed without difficulty. Histologically, the tumor was composed of spindle-shaped cells with an interlacing bundle pattern, and immunohistochemical examination showed that it was positive for myeloid stem cell antigen (CD34), but negative for HHF35 and S-100 protein. These findings were consistent with a GIST lacking myogenic features and neural attributes. The patient had an uneventful postoperative course, and was free of recurrence when last seen 11 months after his operation.

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“…About half of all omental GISTs are misdiagnosed as extra mucosal tumors of the stomach. [7][8][9] Additionally, omental EGISTs seem to be morphologically and immunohistochemically identical to their gastric and intestinal counterparts. They are cellular tumors consisting of elongated spindle and epithelioid cells that are typically positive for CD117 and, less consistently, for CD34.…”

Section: Gistsmentioning

confidence: 95%

Extra - Intestinal Gastrointestinal Stromal Tumor of Omentum

Basnet

Lakhey

2014

J Pathol Nep

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Gastrointestinal stromal tumors are rare tumors, constituting less than 3% of all gastrointestinal malignant neoplasms but are the most common mesenchymal tumors of the gastrointestinal tract. Approximately 10% of gastrointestinal stromal tumors are extraintestinal and mostly arise from the mesentery or omentum. Here we report a rare case of an extraintestinal gastrointestinal stromal tumor of mesentery. Morphological and immunohistochemical features led to a diagnosis of extra-gastrointestinal stromal tumor.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11610 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 682-684

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A Case of Primary Leiomyosarcoma of the Lesser Omentum

Cited by 3 publications

References 2 publications

Extra-Gastrointestinal Stromal Tumor of the Omentum: A Rare Case Report and Review of the Literature

Extra-Gastrointestinal Stromal Tumor of the Omentum: A Rare Case Report and Review of the Literature

Gastrointestinal Stromal Tumor of the Lesser Omentum: Report of a Case

Extra - Intestinal Gastrointestinal Stromal Tumor of Omentum

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