A Case of Primary Duodenal Carcinoma Presenting as a Gastric Submucosal Tumor

Kubota, Koichi; Yagawa, Hirokazu; Umeda, Hiroshi; Matsumoto, Norio; Kumazawa, Kenichi; Naritaka, Yoshihiko; Otani, Yoichi; Kikuchi, Tomomitsu; Haga, Shunsuke; Ogawa, Kenji; Kajiwara, Tetsuro

doi:10.3919/ringe1963.51.1763

Cited by 2 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our analysis of these 20 cases shows they involved 15 men and 5 women, with a mean age of 67.4 years (range 39–85 years) [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23] (table 1). Eight tumors were located in the first portion of the duodenum and twelve in the second portion.…”

Section: Discussionmentioning

confidence: 99%

“…In 2002, Akino et al summarized 16 cases of carcinoma arising from Brunner's gland [ 3 , 4 , 9 , 11 , 14 , 19 , 26 , 27 ], and five further cases were later reported [ 20 , 21 , 22 , 23 ]. Our analysis of these 20 cases shows they involved 15 men and 5 women, with a mean age of 67.4 years (range 39–85 years) [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ] (table 1 ). Eight tumors were located in the first portion of the duodenum and twelve in the second portion.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, tumors arising from Brunner's gland are extremely rare [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], and only two reports describe the preoperative observation period [11, 21]. Here we report on an extremely rare case of primary duodenal carcinoma arising from Brunner's gland in a patient who had been under observation for 17 years.…”

Section: Introductionmentioning

confidence: 99%

“…The increased use of endoscopies in recent years has led to an increase in the identification of duodenal lesions; however, primary duodenal carcinomas remain comparatively rare and account for only 0.3% of digestive organ carcinomas [ 1 , 2 , 3 ]. Furthermore, tumors arising from Brunner's gland are extremely rare [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ], and only two reports describe the preoperative observation period [ 11 , 21 ]. Here we report on an extremely rare case of primary duodenal carcinoma arising from Brunner's gland in a patient who had been under observation for 17 years.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Carcinoma Arising from Brunner’s Gland in the Duodenum after 17 Years of Observation – A Case Report and Literature Review

Koizumi

Sata

Yoshizawa

et al. 2007

Case Rep Gastroenterol

View full text Add to dashboard Cite

A 60-year-old man presented with melena and hematemesis in 1984. Esophagogastroduodenoscopy (EGD) detected a small protruding lesion in the duodenal bulb, which was diagnosed as Brunner’s adenoma. No significant change was detected in subsequent annual EGD and biopsies for 10 years, after which the patient was not observed for 7 years. The patient presented with melena again in 2001. The lesion had changed shape to become a 10 mm sessile tumor with a central depression, and following a biopsy was diagnosed as an adenocarcinoma. The patient underwent partial resection of the duodenum. Histopathological assessment showed acidophilic cells with swollen nuclei, and clear cells forming a tubular or papillary tubule in the mucosal lamina propria and submucosal layer. The tumor cells stained positive for lysozyme, indicating that they arose from Brunner’s gland. The patient showed no sign of recurrence and was disease-free for more than 34 months after surgery. The patient died of pneumonia. This is an extremely rare case of primary duodenal carcinoma arising from Brunner’s gland in a patient observed for 17 years.

show abstract