A Case of Primary Biliary Cirrhosis Associated with Hashimoto's Thyroiditis, Scleroderma and Sjoegren's Syndrome.

Horita, Masakazu; Takahashi, Naohiko; Seike, Masataka; Nasu, Shinji; Takaki, Ryosaburo

doi:10.2169/internalmedicine.31.418

Cited by 17 publications

(7 citation statements)

References 9 publications

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“…However, the present patient's HLA type was different from the frequent DRB1 0405-DQB1 0401 haplotype observed in type 1 diabetes and AITD (5). Chronic liver disease has also been implicated as a complication of Hashimoto's thyroiditis, and the term "hepatothyroiditis syndrome" has been proposed to describe this condition (6). Thyroid disease is also found in about 10-15% of patients with PBC, and AITD is the most common (7).…”

Section: Discussionmentioning

confidence: 55%

Slowly Progressive Insulin-Dependent Diabetes in a Patient with Primary Biliary Cirrhosis with Portal Hypertension-Type Progression

et al. 2012

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A 73-year-old woman had previously been diagnosed with CREST syndrome, PBC and diabetes. Hepatic fibrosis was not evident, in spite of the transudative ascites and active esophageal varices. ACA were positive, whereas AMA and anti-gp210 antibodies were negative. She showed low urinary excretion of C-peptide and was weakly positive for anti-GAD antibody. She was diagnosed with a form of PBC that progresses via portal hypertension rather than liver failure and with SPIDDM. Her HLA type did not contain risk allele for IDDM or PBC. SPIDDM should be considered when patients with PBC with portal hypertension-type progression develop diabetes.

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Section: Discussionmentioning

confidence: 55%

Slowly Progressive Insulin-Dependent Diabetes in a Patient with Primary Biliary Cirrhosis with Portal Hypertension-Type Progression

et al. 2012

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“…Esto viene corroborado por la frecuencia de agrupaciones HLA DRW3 y HLA B8 en el SS, hipotiroidismo primario, la enfermedad de Basedow y la TH (5,7). Esta asociación ha sido también englobada dentro del síndrome autoinmune múltiple (7)(8)(9)(10)(11). Por eso, es necesario investigar dicho síndrome en pacientes con enfermedad tiroidea y una historia familiar de enfermedades autoinmunes (7).…”

Section: Discussionunclassified

Tiroiditis de Hashimoto y síndrome de Sjögren: ¿Asociación o síndrome múltiple autoinmune?

Santos¹,

Revuelta²,

Cuadros³

et al. 2001

An. Med. Interna (Madrid)

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“…The whole skin can have a yellowish color, connected with a disorder of carotenoid metabolism. Within its reach, there may also be hyperkeratotic areas [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

“…Hypothyroidism can also occur during the treatment of hyperthyroidism with radioiodine or after surgical removal. Less frequently, it is observed in endemic areas of iodine deficiency ( 1 ).…”

Section: Introductionmentioning

confidence: 99%

Morphea and Lichen Sclerosus in a Patient with Hyporthyroidism

Bergler‐Czop

Brzeźińska-Wcisło

2020

ACC

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Thyroid gland is one of the key organs regulating the metabolism of carbohydrates, proteins and fats. Its primary function is connected with increase of the metabolic conversion of the body. Skin lesions are often one of the first symptoms of hypothyroidism. In a 71-year-old patient, skin lesions in the form of thickened areas with severe hyperkeratosis first appeared 12 years before. Eight years before, the patient was diagnosed with hypothyroidism of unknown cause. Upon admission, lesions were observed in the trunk area, left arm and vulva. These lesions had the appearance of brownish spots with hyperkeratosis. Initially, they were localized on the trunk, then involving upper limbs and neck area with time. Significant progression was present in the back area. In the anogenital area, porcelain-white discolorations were observed. Laboratory examinations were normal. During hospital stay, iv. ceftriaxone at a dose of 2.0 g/day for 10 days and intramuscular injection of vitamin B6 were administered, along with 10% urea ointment for hyperkeratosis lesions as topical therapy. The patient had lesions in the form of skin induration and discoloration, with visible, very severe hyperkeratosis, which is not characteristic of changes of the scleroderma and lichen sclerosus type. These lesions caused diagnostic problems due to the atypical clinical appearance.

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A Case of Primary Biliary Cirrhosis Associated with Hashimoto's Thyroiditis, Scleroderma and Sjoegren's Syndrome.

Cited by 17 publications

References 9 publications

Slowly Progressive Insulin-Dependent Diabetes in a Patient with Primary Biliary Cirrhosis with Portal Hypertension-Type Progression

Slowly Progressive Insulin-Dependent Diabetes in a Patient with Primary Biliary Cirrhosis with Portal Hypertension-Type Progression

Tiroiditis de Hashimoto y síndrome de Sjögren: ¿Asociación o síndrome múltiple autoinmune?

Morphea and Lichen Sclerosus in a Patient with Hyporthyroidism

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