A Case of Pocket Fill Causing Baclofen Withdrawal

Wankhede, Vaishali

doi:10.1111/ner.12887

Cited by 2 publications

(2 citation statements)

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“…For example, new pump designs with improved battery life and smaller sizes have been developed, offering increased convenience and comfort for patients. Furthermore, the development of programmable pumps allows for more precise dosing and flexibility in adjusting medication delivery based on individual needs [76][77][78].…”

Section: Advancements In Technologymentioning

confidence: 99%

“…Ongoing research and innovation in the field of intrathecal drug delivery aim to improve treatment outcomes, reduce complications, and expand its applications. Scientists and healthcare professionals are continuously exploring new drugs, delivery techniques, and technologies to advance the field and provide better pain management options for patients [76][77][78].…”

Section: Research and Innovationmentioning

confidence: 99%

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Current Advancements and Complications in Intrathecal Drug Delivery System

MANNAN,

FAHAD,

AMJAD

et al. 2023

Int J Pharm Pharm Sci

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Intrathecal drug delivery systems (IDDS) have emerged as a valuable treatment option for patients with chronic pain who have failed to achieve adequate relief with conventional therapies. These systems provide targeted delivery of medications directly to the cerebrospinal fluid, resulting in improved pain control and reduced systemic side effects. However, the use of IDDS is not without potential complications and considerations that must be addressed to ensure optimal patient outcomes. This comprehensive review examines the various complications associated with IDDS and the considerations that healthcare providers and patients need to be aware of. Surgical complications, such as infection, bleeding, spinal fluid leaks, and nerve damage, are discussed, along with strategies to minimize these risks. Device malfunctions, including pump failure, catheter issues, and electronic problems, are explored, highlighting the importance of regular monitoring and maintenance. Medication-related side effects, such as nausea, sedation, and respiratory depression, are addressed, emphasizing the need for close monitoring and appropriate dosage adjustments. Long-term considerations, including tolerance to medication, physical dependence, and withdrawal symptoms, are also examined, emphasizing the significance of gradual tapering and proper discontinuation protocols. The review underscores the importance of regular follow-up appointments to assess the system's functionality, medication dosages, and patient response to treatment. By proactively managing and addressing complications, healthcare providers can optimize pain relief and minimize adverse effects, ensuring the long-term effectiveness and safety of IDDS.

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Section: Advancements In Technologymentioning

confidence: 99%

Section: Research and Innovationmentioning

confidence: 99%