A Case of Pleomorphic Fibroma of the Skin Presenting as Intradermal Nodule

Slow-Growing Nodule in a Patient With Li-Fraumeni Syndrome: Answer

“…3 Pleomorphic fibroma is successfully treated by shave biopsy or excision; recurrences are rare, and regional extension or metastasis has not been reported. 5 Pleomorphic fibroma has been associated with several cytogenic alterations, including deletion or loss of chromosome 13q and chromosome 17p, the location of tumor suppressor genes RB1 and TP53, respectively. 6 In one study, 100% of cases (7/7) demonstrated loss of chromosome 13q, suggesting loss of RB1 as critical in its pathogenesis.…”

“…3 Pleomorphic fibroma is successfully treated by shave biopsy or excision; recurrences are rare, and regional extension or metastasis has not been reported. 5…”

Cutaneous Pseudolymphoma Caused by an Injury with a Metallic Piece of a Mowing Machine Containing Tungsten

“…A review of the English and Japanese literature including the present case identified five cases of CPL caused by injuries with pieces of metal-containing tungsten [ Supplementary Table 1 ]. [ 2 3 ] All cases were adult males, and four cases were caused by blades of saws or mowing machines. The interval from injury to initial presentation varied from three months to five years.…”