A 49-year-old male presented to our hospital with a liver tumor. CT revealed a slightly enhanced liver tumor of 30 mm in diameter in segment 6. The patient had a history of surgery for ameloblastoma 24 years ago and for metastatic lung tumors 4 years ago. Thus, laparoscopic partial liver resection was performed based on medical guidelines. Pathologically, the tumor was diagnosed as metastatic ameloblastoma. This case serves as an important reminder to consider metastatic ameloblastoma in an investigation of possible causes of a liver tumor after treatment for ameloblastoma.