A case of paroxetine-induced akathisia

Olivera, Arturo A.

doi:10.1016/0006-3223(96)84504-5

Cited by 10 publications

(5 citation statements)

References 3 publications

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“…Anti-dopaminergic anti-emetics (such as prochlorperazine and metaclopramide), as well as dopamine-depleting agents (reserpine and tetrabenazine, which impede reuptake of dopamine into presynaptic vesicles), have also been reported to commonly cause akathisia. 42,43 Antidepressant-induced akathisia There is growing awareness that akathisia can occur during treatment with antidepressant drugs, of which SSRIs have received the most reports of an association, [44][45][46][47][48][49][50][51][52] with relatively fewer reports of tricyclic antidepressants (TCAs) 53,54 or monoamine oxidase inhibitors (MAOIs). 54 Other drug-induced akathisia…”

Section: Antipsychotic-induced Akathisiamentioning

confidence: 99%

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The clinical challenges of akathisia

et al. 2015

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Akathisia is one of the most vexing problems in neuropsychiatry. Although it is one of the most common side effects of antipsychotic medications, it is often difficult to describe by patients, and is difficult to diagnose and treat by practitioners. Akathisia is usually grouped with extrapyramidal movement disorders (ie, movement disorders that originate outside the pyramidal or corticospinal tracts and generally involve the basal ganglia). Yet, it can present as a purely subjective clinical complaint, without overt movement abnormalities. It has been subtyped into acute, subacute, chronic, tardive, withdrawal-related, and "pseudo" forms, although the distinction between many of these is unclear. It is therefore not surprising that akathisia is generally either underdiagnosed or misdiagnosed, which is a serious problem because it can lead to such adverse outcomes as poor adherence to medications, exacerbation of psychiatric symptoms, and, in some cases, aggression, violence, and suicide. In this article, we will attempt to address some of the confusion surrounding the condition, its relationship to other disorders, and differential diagnosis, as well as treatment alternatives.

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Section: Antipsychotic-induced Akathisiamentioning

confidence: 99%

“…There is growing awareness that akathisia can occur during treatment with antidepressant drugs, of which SSRIs have received the most reports of an association, 44 – 52 with relatively fewer reports of tricyclic antidepressants (TCAs) 53 , 54 or monoamine oxidase inhibitors (MAOIs) 54 …”

Section: Etiology and Epidemiologymentioning

confidence: 99%

The clinical challenges of akathisia

et al. 2015

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“…Yan etki olgu bildirimlerinin gözden geçirildiği bir derlemede bupropion kullanımına bağlı iki akatizi olgusu bildirilmektedir (17). Imboden ve Hatzinger agomelatin ve duloksetin kullanımı sonrası akatizi gelişen birer olgu bildirmişlerdir (35).…”

Section: Epidemiyolojiunclassified

“…SSRI'ların tetiklediği akatizi genellikle ilacın alınmaya başlanmasından veya doz artırımından sonraki birkaç günlük veya birkaç haftalık süreçte ortaya çıkmaktadır. Olivera tek doz sertralin alımını takip eden iki saat içinde akatizi gelişen bir hastayı bildirmiştir(35).Alvagi ve Kumar ise fluoksetin dozunun artırımından dört hafta sonra akatizi gelişen bir hastayı bildirmiştir(36). Bu bulgular ilaca maruziyet sonrasında akatizi gelişmesi için geçen sürenin hastalar arasında farklılık gösterdiğini düşündürmektedir.Antidepresanlar ile ilişkili akatizide vurgulanmasıgerek en önemli noktalardan birisi ise suisid girişimi ile olan ilişkisidir.…”

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Antidepressants and akatishia

Albayrak¹,

Kuloğlu²

2013

JMOOD

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Antidepresanlar ve akatiziAntidepresanlarla ilişkilendirilen başağrısı, bulantı veya kusma, ajitasyon, sedasyon, uykusuzluk ve cinsel işlev bozukluğu gibi yan etkiler iyi bilinmesine karşın antidepresanlar ve akatizi arasındaki ilişkiye dair bilgilerimiz sınırlıdır. Akatizi ciddi bir yan etkidir ve genellikle tipik antipsikotiklerin yan etkisi olarak kabul edilir. Akatiziyi fark etmek olası intihar girişimlerini önlemek açısından oldukça önemlidir. Bu yazıda akatizi hakkında genel bilgi vermeyi ve antidepresan tedaviyle olan ilişkisini gözden geçirmeyi amaçladık.

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“…Olivera described a 40-year-old woman who developed akathisia (a form of restlessness in which there is the inability to sit still, an urge to move about constantly and a feeling of muscular quivering) after three days of taking paroxetine 20 mg daily. 2 ADRAC has received nine reports of akathisia where an SSRI was the only suspected drug since 17 February 1993. Fluoxetine was the suspected drug in six reports, paroxetine in two and sertraline in one.…”

Section: Akathisiamentioning

confidence: 99%

Movement disorders with selective serotonin reuptake inhibitors

1997

Medical Journal of Australia

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A case of paroxetine-induced akathisia

Cited by 10 publications

References 3 publications

The clinical challenges of akathisia

The clinical challenges of akathisia

Antidepressants and akatishia

Movement disorders with selective serotonin reuptake inhibitors

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