A Case of Paraneoplastic Syndrome Associated with Pancreatic Cancer Presenting as Rheumatoid Arthritis

Kim, Young-il; Choi, S.Y.; Lee, Hojun; Lee, Kyung-Eun; Lee, Sung-Ji; Seo, Seong-Rye; Kim, Tae‐Jong; Park, Yong-Wook; Lee, Shin-Seok

doi:10.4078/jrd.2011.18.1.32

Cited by 1 publication

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“…Typical features of paraneoplastic rheumatic syndrome are asymmetrical arthritis, negative finding of RF, elderly patients aged less than 50 years, and systemic symptoms such as fever, weight loss, and night sweat. But various symptoms are appeared in paraneoplastic rheumatic syndrome, especially symmetric arthralgia mimics RA in other study and cases [5,8]. As patients with rheumatic disease have a higher incidence of certain malignant lymphoma compared to healthy people, it is necessary to check whether rheumatic disease is involved, even when paraneoplastic syndrome is suspected.…”

Section: Discussionmentioning

confidence: 97%

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A Case of Primary Bone Marrow Diffuse Large B-cell Lymphoma Presenting with Polyarthritis

Kim

Park

et al. 2016

J Rheum Dis

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Polyarthritis is a common manifestation of rheumatologic disorders; however, paraneoplastic arthropathies also arise as polyarthritis or polymyalgia, particularly in patients with myelomas, lymphomas, acute leukemia, and solid tumors. Because paraneoplastic syndromes, in some instances, might be manifested before a cancer diagnosis, they are difficult to diagnose and are often misdiagnosed. We experienced a 63-year-old female patient who had nonspecific arthritis on both hands and feet accompanied by fever. She had been diagnosed as rheumatoid arthritis and treated with prednisolone and disease modifying anti-rheumatic drugs (DMARDs) including methotrexate and anti-tumor necrosis factor agents. Her arthritis did not respond with anti-rheumatic treatment and diffuse large B-cell lymphoma was diagnosed by bone marrow biopsy. After 6 cycles of chemotherapy, her arthritis was improved as well as underlying lymphoma. (J Rheum Dis 2016;23:256-260)

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Section: Discussionmentioning

confidence: 97%

“…In Korea, there have been a few cases of paraneoplastic syndrome appearing as a form of arthritis reported and most of them are solid tumors such as ovarian cancer, pancreatic cancer, and metastatic adenocarcinoma of unknown primary site [4][5][6]. However, hematologic malignancy as an underlying disease is rarely reported.…”

Section: Introductionmentioning

confidence: 99%

A Case of Primary Bone Marrow Diffuse Large B-cell Lymphoma Presenting with Polyarthritis

Kim

Park

et al. 2016

J Rheum Dis

View full text Add to dashboard Cite

show abstract

A Case of Paraneoplastic Syndrome Associated with Pancreatic Cancer Presenting as Rheumatoid Arthritis

Cited by 1 publication

References 14 publications

A Case of Primary Bone Marrow Diffuse Large B-cell Lymphoma Presenting with Polyarthritis

A Case of Primary Bone Marrow Diffuse Large B-cell Lymphoma Presenting with Polyarthritis

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