A Case of Organoaxial Gastric Volvulus

Congenital Diaphragmatic Hernia with Gastric Volvulus and Splenic Herniation: An Unusual Delayed Presentation in a Six- Month Child

“…9-11 Organoaxial volvulus, as seen in our case, is the most common type seen in 60% of volvulus cases. In organoaxial volvulus, the rotation occurs along the cardio-pylorus axis due to abnormal mobility and deficient fixation at the hiatus of the stomach 12 .A diaphragmatic hernia is frequently associated with this type 13 .In mesenteroaxial volvulus, the stomach rotates around an axis between the greater and lesser curvatures. Finally, in the combined type, the stomach rotates about both axes 12 .Anomalies in the ligaments could also lead to splenic herniation as seen in the index case, although it is a rare finding in the postneonatal age 14 .Some authors report that a mobile spleen could potentially cause the volvulus by drawing the gastric fundus downwards in an erect position.…”

“…12 A diaphragmatic hernia is frequently associated with this type. 13 In mesenteroaxial volvulus, the stomach rotates around an axis between the greater and lesser curvatures. Finally, in the combined type, the stomach rotates about both axes.…”

Multicomponent Pyrazole Synthesis from Alkynes, Nitriles, and Titanium Imido Complexes via Oxidatively Induced N–N Bond Coupling

“…We propose the mechanism for N-N coupling in Figure 8 based on the stoichiometric oxidations of 7a,b, the 2H-azirine 8a ring-opening reactivity with various Ti oxidation states, and the reactivity and electrochemistry of 9a. First, multicomponent coupling of a Ti imido with an alkyne and nitrile via the previously established [2+2]/insertion mechanism 44,49 gives diazatitanacycle A, arbitrarily considered to be in the "default" oxidation state of this system. As demonstrated in the series of redox experiments above ( Figure 5, reaction II), A can also be accessed via ring-opening of 2-imino-2H-azirines by a Ti II precursor such as Cp 2 Ti(BTMSA).…”

“…Our group has produced several examples of early transition metal-catalyzed oxidative aminations of alkynes for the synthesis of pyrroles, [36][37][38][39][40] which proceeds through an electrocyclic reductive elimination to form a C-N bond from an azatitanacyclohexadiene intermediate ( Figure 1c, bottom right). 41 We envisioned that reaction of an analogous diazatitanacyclohexadiene 42 ' 43 -formed from the reaction between a nitrile and the common azatitanacyclobutene intermediate [44][45][46][47][48][49][50][51][52][53][54] -could result in a formal N-N bond reductive elimination to produce multisubstituted pyrazoles, either through catalytic turnover with azobenzene as an oxidant or by further reaction with an exogenous oxidant ( Figure 1c, bottom left). Herein, we report an example of oxidation-induced N-N bond reductive elimination, yielding pyrazoles from diazatitanacyclohexadienes (Figure 1c, top).…”