A Case of Occupational Asthma in a Plastic Injection Process Worker

Lee, Jong Suk; Kwak, Hyun Seok; Choi, Byung Soon; Park, So Young

doi:10.1186/2052-4374-25-25

Cited by 8 publications

(8 citation statements)

References 26 publications

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“…Prolonged working hour and excessive OPA are major occupational problems in Korea, with corresponding increases in the compensable CVD [32]. As adverse HRV is a preclinical biomarker for CVD including coronary heart disease, stroke, dysrhythmia, and sudden death [2, 21], the findings of this study potentially indicate that high OPA could cause CVD.…”

Section: Discussionmentioning

confidence: 90%

Effects of high occupational physical activity, aging, and exercise on heart rate variability among male workers

Kang

Kim

et al. 2015

Ann of Occup and Environ Med

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ObjectivesEffects of aging and leisure time physical activity (LPA) might influence the effect of occupational physical activity (OPA) on risk for cardiovascular disease (CVD). This study was conducted to determine whether OPA affects CVD after controlling the effects of LPA and other risk factors for CVD such as job stress.MethodsParticipants were 131 male Korean manual workers. Tests for heart rate variability (HRV) were conducted for five minutes in the morning at work. We defined OPA as the combined concept of relative heart rate ratio (RHR), evaluated using a heart rate monitor.ResultsWhereas high OPA was not related to any HRV items in the younger age group, high OPA was associated with an increased number of low-value cases among all HRV items in older workers. Exercise had beneficial effects only in the younger group. After controlling for exercise and other risk factors, the odds ratios of the root-mean square of the difference of successive normal R-R intervals (rMSSD) and high frequency band power (HF) among the older age and high OPA group compared with the younger age and low OPA group were 64.0 and 18.5, respectively. Social support and shift work were independent risk factors in HRV.ConclusionsOPA in aging workers increases CVD risks. This study provides support for the need for protection of aging workers from physical work overload, and indicates the need for further study of optimal limits of OPA.

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Section: Discussionmentioning

confidence: 90%

Effects of high occupational physical activity, aging, and exercise on heart rate variability among male workers

Kang

Kim

et al. 2015

Ann of Occup and Environ Med

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“…Note that some of the compounds identified in chamber air during 3-D and laser printing are associated with asthma. For example, styrene, [7] and carbonyl compounds including 4- oxopentanal are known or suspected immune-mediated asthmagens. [8,12,13,30–32] Further, ozone is known to transform styrene and unsaturated VOCs such as d-limonene into secondary organic aerosols.…”

Section: Resultsmentioning

confidence: 99%

“…Some VOCs are respiratory and mucous membrane irritants [2,6] or allergic asthmagens. [7,8] Ozone is a lung irritant and a reactive gas that may alter indoor air chemistry by interacting with unsaturated VOCs to form secondary organic aerosols and reactive products such as carbonyl compounds. [9–11] Carbonyl compounds such as aldehydes and ketones are associated with development of asthma.…”

Section: Introductionmentioning

confidence: 99%

Characterization of chemical contaminants generated by a desktop fused deposition modeling 3-dimensional Printer

Stefaniak

LeBouf

et al. 2017

Journal of Occupational and Environmental Hygiene

100

133

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Printing devices are known to emit chemicals into the indoor atmosphere. Understanding factors that influence release of chemical contaminants from printers is necessary to develop effective exposure assessment and control strategies. In this study, a desktop fused deposition modeling (FDM) 3-dimensional (3-D) printer using acrylonitrile butadiene styrene (ABS) or polylactic acid (PLA) filaments and two monochrome laser printers were evaluated in a 0.5 m3 chamber. During printing, chamber air was monitored for vapors using a real-time photoionization detector (results expressed as isobutylene equivalents) to measure total volatile organic compound (TVOC) concentrations, evacuated canisters to identify specific VOCs by off-line gas chromatography-mass spectrometry (GC-MS) analysis, and liquid bubblers to identify carbonyl compounds by GC-MS. Airborne particles were collected on filters for off-line analysis using scanning electron microscopy with an energy dispersive x-ray detector to identify elemental constituents. For 3-D printing, TVOC emission rates were influenced by a printer malfunction, filament type, and to a lesser extent, by filament color; however, rates were not influenced by the number of printer nozzles used or the manufacturer’s provided cover. TVOC emission rates were significantly lower for the 3-D printer (49–3552 μg h−1) compared to the laser printers (5782–7735 μg h−1). A total of 14 VOCs were identified during 3-D printing that were not present during laser printing. 3-D printed objects continued to off-gas styrene, indicating potential for continued exposure after the print job is completed. Carbonyl reaction products were likely formed from emissions of the 3-D printer, including 4-oxopentanal. Ultrafine particles generated by the 3-D printer using ABS and a laser printer contained chromium. Consideration of the factors that influenced the release of chemical contaminants (including known and suspected asthmagens such as styrene and 4-oxopentanal) from a FDM 3-D printer should be made when designing exposure assessment and control strategies.

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“…Table summarizes five articles describing 11 cases of respiratory illness occurring among workers exposed to rubber manufacturing emissions at five facilities located in the United States ( n = 2), Canada (1), Korea (1), and Ethiopia (1) . Ten of the cases occurred among males.…”

Section: Resultsmentioning

confidence: 99%

Non‐malignant respiratory disease among workers in the rubber manufacturing industry: A systematic review and meta‐analysis

Thapa

Tomasi

Cox‐Ganser

et al. 2019

American J Industrial Med

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Background: Non-malignant respiratory disease (NMRD) cases have occurred among rubber manufacturing workers. We examined exposure to rubber manufacturing emissions as a risk factor for NMRD.Methods: From a systematic literature review, we identified case reports and assessed cross-sectional and mortality studies for strength of evidence of positive association (strong, intermediate, non-significant positive association, none) between exposure to rubber manufacturing emissions and NMRD-related morbidity and mortality, and conducted two meta-analyses. Results:We analyzed 62 articles. We identified 11 cases of NMRD. Nine (30%) of 30 cross-sectional studies and one (4%) of 26 mortality studies had strong evidence. The summary odds ratio and SMR for the cross-sectional and mortality meta-analyses were 3.83 (95% confidence interval [CI], 2.28-6.51) and 0.90 (95%CI, 0.82-0.99), respectively. Conclusion:Available evidence supports rubber manufacturing emissions as a potential risk factor for NMRD-related morbidity. Further investigations with longer follow-up periods and inclusion of short-tenured workers could further define risks for NMRD and identify prevention strategies. K E Y W O R D Schronic bronchitis, chronic obstructive pulmonary diseases, emphysema, eosinophilia, nonmalignant respiratory disease, occupational asthma, occupational lung disease, rubber

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A Case of Occupational Asthma in a Plastic Injection Process Worker

Cited by 8 publications

References 26 publications

Effects of high occupational physical activity, aging, and exercise on heart rate variability among male workers

Effects of high occupational physical activity, aging, and exercise on heart rate variability among male workers

Characterization of chemical contaminants generated by a desktop fused deposition modeling 3-dimensional Printer

Non‐malignant respiratory disease among workers in the rubber manufacturing industry: A systematic review and meta‐analysis

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