A case of neonatal allo-immune thrombocytopenia due to a new platelet antigen (YuKa).

勲, 松田; 温美, 菰田; 修, 福森田; 琢也, 岩崎; 琢磨, 松田; 洋一, 柴田

doi:10.3925/jjtc1958.32.335

Cited by 1 publication

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The development of this gel layer stimulates bone formation. [3][4][5][6] The observation that Bioglass enhances bone formation has prompted investigators to evaluate in limited clinical traits 7 its utility as an implant coating. Preliminary results where Bioglass was used as a coating of revision femoral stems so far have been encouraging.…”

Section: Introductionmentioning

confidence: 99%

Effect of particulate bioactive glass on human synoviocyte cultures

Bendall

Gaies

Frondoza

et al. 1998

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

Bioglass is a resorbable glass material that has been shown to induce osteoblast proliferation as well as bone matrix production in vitro. Its physico-chemical properties have been reported to be suitable for use as an implant coating for arthroplasty. However, Bioglass is a ceramic material that can fragment into particulate debris in vivo. The effect of particulate Bioglass on tissue cells has not been defined. In order to determine the biologic response to particulate Bioglass, we tested its effect on human synoviocytes in a cell culture model. At the concentrations of 1.0 and 10, micrograms/mL, particulate Bioglass (sizes ranging from approximately 0.5 to 80 microns) had a low cytotoxic effect. However, these concentrations induced secretion of TNF alpha. The observation that particulate Bioglass elicits release of inflammatory cytokines suggests that the development of this bioceramic implant coating should address techniques that would minimize the generation of particulates.

show abstract