A Case of Multiple Pilar Tumors and Pilar Cysts Involving the Scalp and Back

Cytodiagnosis of Simple and Proliferating Trichilemmal Cysts

“…Pilar cysts can also give rise to proliferating trichilemmal cysts and pilar tumors. 4,6,9 Thus, if aware of the cytologic features of pilar cysts, a cytologist can check for the above possibilities.…”

“…7,8 Pilar cysts frequently occur on the scalp, are often multiple and can progress to pilar tumors. 4,6,7 Pilar tumors are the neoplastic counterparts, also occurring on the scalp, but are usually solitary and thought to arise through progression of pilar cysts; hence, they are better called proliferating trichilemmal cysts. 1,6 Pilar tumors can mimic a variety of cutaneous benign and malignant lesions, including squamous cell carcinoma.…”

Multicentric calcified trichilemmal cysts with alopecia universalis affecting siblings

“…[4] Multiple trichilemmal cysts are known to occur within the scalp, but occurrence in a multicentric distribution is extremely rare. [5] One such rare case of multicentric trichilemmal cysts associated with dystrophic calcification and familial occurrence is reported here and the literature reviewed.…”

Mapping of hereditary trichilemmal cyst(TRICY1)to chromosome 3p24-p21.2 and exclusion of β-CATENINandMLH1

“…It occurs predominantly on the scalp [McGavran and Binnington, 1966;Pinkus, 1969], is easily enucleated and appears as a firm, smooth, whitewalled cyst without a punctum [Leppard and Sanderson, 1976;Leppard et al, 1977]. Benign, relatively uncommon, invasive proliferating trichilemmal tumors [Naik et al, 1990;Hendricks et al, 1991;Laing et al, 1991;Reis et al, 1993;Sleater et al, 1993] and rare cases of metastasizing proliferating trichilemmal cysts [Weiss et al, 1995;Park et al, 1997] have been reported. This is an autosomal dominant trait [Leppard et al, 1977], but it does not yet have its separate entry in the OMIM database.…”